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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A2275-73Q2.50 | 50 µg | - | - |
3 - 19 business days* |
503.00€
|
||
A2275-73Q2.100 | 100 µg | - | - |
3 - 19 business days* |
819.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The beta-amyloid peptide (beta A4), proteolytically released from the amyloid precursor protein... more
Product information "Anti-Amyloid beta, amino acids 1-40, CT, FITC conjugated, clone 6D3"
The beta-amyloid peptide (beta A4), proteolytically released from the amyloid precursor protein (APP), is the principal component of senile plaques in Alzheimer's disease. , Cleavage of APP by alpha-secretase or alternatively by beta secretase leads to generation and extracellular release of soluble APP peptides, S-APP-alpha and S-APP-beta, respectively, and the retention of corresponding membrane anchored C-terminal fragments, C83 and C99. Subsequent processing of C83 by gamma-secretase yields P3 peptides. This is the major secretory pathway and is nonamyloidogenic. Alternatively, presenilin/nicastrin-mediated gamma-secretase processing of C99 releases the amyloid beta proteins, amyloid- beta 40 (Abeta40) and amyloid-beta 42 (Abeta42), major components of amyloid plaques, and the cytotoxic C-terminal fragments, gamma-CTF(50), gamma-CTF(57) and gamma- CTF(59). Applications: Suitable for use in FLISA and Immunocytochemistry. Other applications have not been tested. Recommended Dilutions: Immunocytochemistry: 1-10ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC conjugates are sensitive to light.
Keywords: | Anti-A4, Anti-APP |
Supplier: | United States Biological |
Supplier-Nr: | A2275-73Q2 |
Properties
Application: | FLISA, ICC |
Antibody Type: | Monoclonal |
Clone: | 6D3 |
Conjugate: | FITC |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Synthetic peptide corresponding to aa 1-40 of C-terminal human -amyloid. |
Database Information
KEGG ID : | K04520 | Matching products |
UniProt ID : | P05067 | Matching products |
Gene ID | GeneID 351 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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