Anti-AMPK alpha 2 / PRKAA2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-F50190-0.08ML	80 µl		-	-	3 - 10 business days*		361.00€
NSJ-F50190-0.4ML	400 µl		-	-	3 - 10 business days*		772.00€

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In 1X PBS, pH 7.4, with 0.09% sodium azide. AMPK alpha 2 is a catalytic subunit of the... more

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Product information "Anti-AMPK alpha 2 / PRKAA2"

In 1X PBS, pH 7.4, with 0.09% sodium azide. AMPK alpha 2 is a catalytic subunit of the AMP-activated protein kinase (AMPK). It acts as a key regulator of glucose homeostasis in liver by phosphorylating CRTC2/TORC2, leading to CRTC2/TORC2 sequestration in the cytoplasm. In response to stress, phosphorylates 'Ser-36' of histone H2B (H2BS36ph), leading to promote transcription. Acts as a key regulator of cell growth and proliferation by phosphorylating TSC2, RPTOR and ATG1/ULK1: in response to nutrient limitation, negatively regulates the mTORC1 complex by phosphorylating RPTOR component of the mTORC1 complex and by phosphorylating and activating TSC2. [UniProt]

Keywords:	Anti-PRKAA2, Anti-Acetyl-CoA carboxylase kinase, Anti-Hydroxymethylglutaryl-CoA reductase kinase, Anti-5'-AMP-activated protein kinase catalytic subunit alpha-2, AMPK alpha 2 Antibody / PRKAA2
Supplier:	NSJ Bioreagents
Supplier-Nr:	F50190

Properties

Application:	WB, ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Portion of amino acids 476-507 from the human protein
Format:	Purified