224 products were found matching "K07198"!
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Metformin (hydrochloride)
Item number: Cay13118-5
Metformin is a biguanide with diverse biological activities. Metformin (250 mg/kg, i.p.) increases hepatic AMPK activity and reduces blood glucose by more than 50% in a liver kinase B1-dependent manner in mice fed normal and high-fat diets, respectively, and reduces blood glucose by 40% in ob/ob mice. It reduces...
| Keywords: | 1,1-Dimethylbiguanide hydrochloride, N,N-dimethyl-imidodicarbonimidic diamide, monohydrochloride |
| Application: | AMPK activator |
| CAS | 1115-70-4 |
| MW: | 165.6 D |
From 32.00€
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Anti-PRKAA1
Item number: ABS-KC-3132.100
Protein function: Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits...
| Keywords: | Anti-5'-AMP-activated protein kinase catalytic subunit alpha-1, Anti-AMPK subunit alpha-1, Anti-Acetyl-CoA carboxylase... |
| Application: | IHC |
| Host: | Mouse |
| Species reactivity: | human |
From 206.00€
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Anti-PRKAA1
Item number: ABS-OC-502.100
Protein function: Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits...
| Keywords: | Anti-5'-AMP-activated protein kinase catalytic subunit alpha-1, Anti-AMPK subunit alpha-1, Anti-Acetyl-CoA carboxylase... |
| Application: | IHC |
| Host: | Mouse |
| Species reactivity: | human |
From 206.00€
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Anti-PRKAA1
Item number: ABS-KC-3363.100
Protein function: Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits...
| Keywords: | Anti-5'-AMP-activated protein kinase catalytic subunit alpha-1, Anti-AMPK subunit alpha-1, Anti-Acetyl-CoA carboxylase... |
| Application: | IP |
| Host: | Mouse |
| Species reactivity: | human |
From 206.00€
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Anti-AMPK alpha2
Item number: E-D-AB-10161L.100
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular...
| Keywords: | Anti-Ampk, Anti-Prkaa2, Anti-ACACA kinase, Anti-HMGCR kinase, Anti-AMPK subunit alpha-2, Anti-Acetyl-CoA carboxylase... |
| Application: | WB, IHC, IF |
| Host: | Rabbit |
| Species reactivity: | human,mouse,rat |
From 109.00€
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BAY-3827
Item number: Cay41448-10
BAY-3827 is an inhibitor of AMP-activated protein kinase (AMPK, IC50 = 1.4 nM at 10 µM ATP). It is selective for AMPK over Aurora A kinase, FMS-related tyrosine kinase 3 (FLT3), and c-Met (IC50s = 1,324, 124, and 788 nM, respectively), p90 ribosomal S6 kinase 2 (RSK2), RSK3, RSK4, p90 ribosomal S6 kinase 1 (MSK1),...
| Keywords: | N-[5-(3,5-dicyano-1,4-dihydro-1,2,6-trimethyl-4-pyridinyl)-6-fluoro-7-methyl-1H-indazol-3-yl]-2-ethyl-benzamide |
| Application: | AMPK inhibitor |
| CAS | 2377576-35-5 |
| MW: | 468.5 D |
From 144.00€
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AICAR
Item number: Cay10010241-50
AICAR is an activator of AMP-activated protein kinase (AMPK). It increases AMPK kinase activity in isolated hepatocytes (EC50 = ~500 µM) and reduces HMG-CoA reductase activity and fatty acid and sterol synthesis in these cells. AICAR (0.5 mM) inhibits insulin-stimulated glucose uptake to 62% of control cells and...
| Keywords: | Acadesine, AICA-Riboside, NSC 105823, 5-amino-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide |
| Application: | AMPK activator |
| CAS | 2627-69-2 |
| MW: | 258.2 D |
From 65.00€
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Dorsomorphin dihydrochloride
Item number: TGM-T6146-10mg
Description: Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on structurally related kinases. Target: AMPK, Autophagy, TGF-beta/Smad. Smiles: Cl.Cl.C(CN1CCCCC1)Oc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccncc1....
| Keywords: | BML-275 dihydrochloride, Compound C 2HCl, Dorsomorphin (Compound C) 2HCl, Compound C dihydrochloride, BML-275 2HCl |
| Application: | AMPK inhibitor |
| CAS | 1219168-18-9 |
| MW: | 472.41 D |
From 31.00€
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GSK621
Item number: TGM-T6854-100mg
Description: GSK621 is a specific and potent AMPK activator. Target: Autophagy, Apoptosis, AMPK. Smiles: COc1cccc(c1)-n1c(=O)[nH]c2cc(Cl)n(-c3ccc(cc3)-c3cccc(OC)c3O)c2c1=O. References: Sujobert P, et al. Cell Rep. 2015, 11(9), 1446-1457.
| Application: | AMPK activator |
| CAS | 1346607-05-3 |
| MW: | 489.91 D |
From 49.00€
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O-304
Item number: TGM-T7362-100mg
Description: O-304 is a pan-activator of AMP-activated protein kinase (AMPK). Target: AMPK. Smiles: Clc1ccc(Cn2sc(NC(=O)c3ccc(Cl)cc3)nc2=O)cc1. References: Steneberg, Pär, Lindahl E , Dahl U , et al. PAN-AMPK activator O304 improves glucose homeostasis and microvascular perfusion in mice and type 2 diabetes...
| Application: | AMPK activator |
| CAS | 1261289-04-6 |
| MW: | 380.25 D |
From 60.00€
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Metformin-d6 hydrochloride
Item number: TGM-T73712-10mg
Description: Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) is a deuterated form of Metformin that can be used to study Metformin metabolism in vivo, and is often used as an internal standard for Metformin.ccc_R08 can be used to study HBV infection.ccc_R08 can be used to study HBV infection. Smiles:...
| Keywords: | 1,1-Dimethylbiguanide-d6 hydrochloride |
| Application: | Internal standard, AMPK activator |
| CAS | 1185166-01-1 |
| MW: | 171.66 D |
From 93.00€
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MOTS-c
Item number: TGM-T77782-50mg
Description: MOTS-c is a mitochondria-derived polypeptide (MDP) that has anti-damage and anti-inflammatory effects by activating the AMPK pathway and inhibiting the MAP kinase-c-fos signaling pathway. Target: Others. Smiles:...
| Application: | Mitochondria-derived peptide, AMPK promoter |
| CAS | 1627580-64-6 |
| MW: | 2174.6 D |
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