Anti-alpha Tubulin, clone 2H2

Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers .Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. Protein function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:34996871). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms (PubMed:34996871). Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha- tubulin (PubMed:34996871). [The UniProt Consortium]