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Anti-Tubulin, alpha
Anti-Tubulin, alpha

Item number: 600-401-880

Protein function: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [The UniProt Consortium]
Keywords: Anti-TUBA1B, Anti-Tubulin K-alpha-1, Anti-Tubulin alpha-1B chain, Anti-Alpha-tubulin ubiquitous, Anti-Tubulin...
Application: WB, ELISA
Reactivity: Human
411.00€ *
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Labeled Tubulin-Alexa Fluor(R) 488
Labeled Tubulin-Alexa Fluor(R) 488

Item number: PUR-048805-0.1

Source: Bovine Brain Material Labeled Tubulin-Alexa Fluor(R) 488 is generated by reacting Alexa Fluor(R) 488 NHS Ester (Thermo Fisher A20100) with Cycled Tubulin(TM) (Cat. No. PUR-032005), thereby covalently linking the dye to random tubulin surface lysines. Cycled Tubulin(TM) is >99% pure and polymerization...
Reactivity: Bovine
From 454.00€ *
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Labeled Tubulin-Alexa Fluor(R) 594
Labeled Tubulin-Alexa Fluor(R) 594

Item number: PUR-059405-0.1

Source: Bovine Brain Material Labeled Tubulin-Alexa Fluor(R) 594 is generated by reacting Alexa Fluor(R) 594 NHS Ester (Thermo Fisher A20104) with Cycled Tubulin(TM) (Cat. No. PUR-032005), thereby covalently linking the dye to random tubulin surface lysines. Cycled Tubulin(TM) is >99% pure and polymerization...
Reactivity: Bovine
From 454.00€ *
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Labeled Tubulin-Alexa Fluor(R) 647
Labeled Tubulin-Alexa Fluor(R) 647

Item number: PUR-064705-0.1

Source: Bovine Brain Material Labeled Tubulin-Alexa Fluor(R) 647 is generated by reacting Alexa Fluor(R) 647 NHS Ester (Thermo Fisher A20106) with Cycled Tubulin(TM) (Cat. No. PUR-032005), thereby covalently linking the dye to random tubulin surface lysines. Cycled Tubulin(TM) is >99% pure and polymerization...
Reactivity: Bovine
From 454.00€ *
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Paclitaxel
Paclitaxel

Item number: Cay10461-5

Paclitaxel, a potent disruptor of microtubules derived from the bark of the Pacific yew tree, is widely used as a chemotherapeutic compound. Tested against a panel of cervical (HeLa), lung (A549), breast (MCF-7), colon (HT-29), ovarian (OVG-1), and pancreatic (PC-Sh) carcinomas, paclitaxel demonstrates IC50 values...
Keywords: NSC 125973, betaS-(benzoylamino)-alphaR-hydroxy-benzenepropanoic acid,...
Application: Apotosis inducer
CAS 33069-62-4
MW: 853.9 D
From 32.00€ *
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Paclitaxel
Paclitaxel

Item number: AG-CN2-0045-M001

Anticancer compound. Chemotherapeutic used in patients with cancer and advanced forms of Kaposi's sarcoma. Microtubule assembly stabilizer. Reversibly binds to polymerized tubulin. Anti-mitotic. Mitotic spindle assembly, chromosome segregation and cell division inhibitor. Induces cell cycle arrest at the G2/M phase....
Keywords: Taxol, BMS 181339-01, NSC 125973
Application: Apoptosis Inducer
CAS 33069-62-4
MW: 853,9 D
From 13.00€ *
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Docetaxel
Docetaxel

Item number: Cay11637-5

Docetaxel is a semisynthetic analog of taxol that inhibits microtubule disassembly (IC50 = 0.2 µM) and inhibits cell replication (IC50 = 0.13 µM). It has proven more effective than taxol in preventing the proliferation of cancer cells. Docetaxel has applications in breast cancer and hormone-refractory prostate...
Keywords: NSC 628503, RP 56976, Taxotel, (alphaR,betaS)-beta-[[(1,1-dimethylethoxy)carbonyl]amino]-alpha-hydroxy-benzenepropanoic...
Application: Microtubule inhibitor
CAS 114977-28-5
MW: 807.9 D
From 40.00€ *
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Colchicine
Colchicine

Item number: Cay9000760-100

Colchicine is an inhibitor of microtubule polymerization (IC50 = 3.2 µM) that binds to tubulin, which disrupts spindle formation during mitosis. It inhibits growth of MCF-7 human breast carcinoma cells with an IC50 value of 13 nM. Colchicine has anti-inflammatory activity, inhibiting neutrophil motility and activity...
Keywords: N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-acetamide
Application: Microtubule polymerization inhibitor
CAS 64-86-8
MW: 399.4 D
From 14.00€ *
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Nocodazole
Nocodazole

Item number: Cay13857-50

Nocodazole reversibly binds tubulin and alters tubulin-associated GTP hydrolysis as well as microtubule dynamics. While nocodazole is used to study many aspects on microtubule function, it is most commonly used to synchronize cell cycling in culture. Typically, nanomolar concentrations of nocodazole reduce both...
Keywords: NSC 238159, Oncodazole, R 17934, N-[6-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-methyl ester-carbamic acid
Application: Microtubule function studies, Cell cycle arrest
CAS 31430-18-9
MW: 301.3 D
From 37.00€ *
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Cucurbitacin B
Cucurbitacin B

Item number: AG-CN2-0472-M001

Off-white powder. Soluble in DMSO. Microtubule polymerization inhibitor. Disrupts F-actin and induces nucleophosmin/B23 translocation, Immunomodulator with antimicrobial, anti-inflammatory and antitumorigenic properties, Induces apoptosis, autophagy and cell cycle arrest at G2/M phase in a range of cancer cell...
Keywords: Cuc B, 1,2-Dihydro-alpha-elaterin, Amarine, NSC 49451, NSC 144154
Application: Microtubule polymerization inhibitor
CAS 6199-67-3
MW: 558,7 D
From 39.00€ *
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Paclitaxel
Paclitaxel

Item number: P1792A.100

Antitumor and antileukemic agent isolated from the bark of the yew tree, Taxus brevifolia. Synonyms: Soluble, CAS No: 33069-62-4, Molecular Formula: C47H51NO14, Molecular Weight: 853.91, Appearance: White powder, Purity: HPLC: ~99%, TLC: ~99%, Solubility: Soluble in DMSO at 200mg/ml, soluble in ethanol at 40mg/ml,...
CAS 33069-62-4
MW: 853.91
From 223.00€ *
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Cycled Tubulin
Cycled Tubulin

Item number: PUR-032005-1

Source: Bovine Brain Material Cycled Tubulin(TM) was isolated by cycling bovine brain homogenate through conditions that promote tubulin polymerization/depolymerization in high salt buffers by an adaptation of the method of Castoldi and Popov (2003). The resulting product is >99% pure and polymerization competent....
Reactivity: Bovine
From 280.00€ *
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