Anti-alpha-Tubulin (C-Term) Rabbit Monoclonal Antibody - Biotinylated (Clone RM113)

alpha-Tubulin is a cytoskeletal protein and constituent of microtubules, a cytoskeletal assembly that has roles in a variety of cellular processes, including cell motility, division, differentiation, and intracellular transport. alpha-Tubulin is highly conserved in eukaryotes and expressed in a cell- and isotype-specific manner. There are eight human alpha-tubulin isotypes that consist of an N-terminal domain, which binds GTP and is required for microtubule self-assembly, and a variable C-terminal tail, which contains interaction sites for microtubule-associated proteins (MAPs) and is subject to a variety of post-translational modifications that regulate microtubule function and stability. Cayman's alpha-Tubulin (C-Term) Rabbit Monoclonal Antibody - Biotinylated (Clone RM113) can be used for immunocytochemistry (ICC) and Western blot (WB) applications. The antibody recognizes alpha-tubulin at approximately 50 kDa.Synonyms: alpha-Tubulin Chain. Immunogen: A peptide corresponding to the C-terminus of alpha-Tubulin. Clone Designation: RM113. MW: ~50 kDa. Formulation: (Request formulation change), 50 µl of protein A-affinity purified from an animal origin-free culture supernatant. Storage Buffer: PBS with 50% glycerol, 1% BSA, and 0.09% sodium azide. Host: Rabbit. Isotype: IgG. Applications: ICC, WB. Cross Reactivity: (+) alpha-Tubulin 1A, (+) alpha-Tubulin 1B.