Anti-AKT1 (v-akt Murine Thymoma Viral Oncogene Homolog 1, C-AKT, MGC99656, PKB, PRKBA, Protein kinas

Anti-AKT1 (v-akt Murine Thymoma Viral Oncogene Homolog 1, C-AKT, MGC99656, PKB, PRKBA, Protein kinas
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A1125-05P.100 100 µl - -

3 - 19 business days*

796.00€
 
Serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum... more
Product information "Anti-AKT1 (v-akt Murine Thymoma Viral Oncogene Homolog 1, C-AKT, MGC99656, PKB, PRKBA, Protein kinas"
Serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific. In the developing nervous system AKT is a critical mediator of growth factor induced neuronal survival. Survival factors can suppress apoptosis in a transcription independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene. Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Western Blot: 1:1000, Optimal dilutions to be determined by the researcher. Positive Control: HEK293 cell lysate. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: EC=2.7.11.1, Anti-PKB alpha, Anti-Proto-oncogene c-Akt, Anti-Protein kinase B alpha, Anti-RAC-alpha serine/threonine-protein kinase
Supplier: United States Biological
Supplier-Nr: A1125-05P

Properties

Application: IP, WB
Antibody Type: Monoclonal
Clone: 10F626
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Sythetic peptide corresponding to the C-terminal aa466-480, C-RPHFPQFSYSASGTA of rat Akt1/PKB alpha (KLH).
Format: Supernatant

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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