Anti-AKT1

Anti-AKT1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
029942.100 100 µl - -

3 - 19 business days*

477.00€
 
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in... more
Product information "Anti-AKT1"
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene. Applications: Western Bloting: 1:500-1:2000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-PKB, Anti-AKT1, Anti-PKB alpha, EC=2.7.11.1, Anti-RAC-PK-alpha, Anti-Protein kinase B, Anti-Proto-oncogene c-Akt, Anti-Protein kinase B alpha, Anti-RAC-alpha serine/threonine-protein kinase
Supplier: United States Biological
Supplier-Nr: 029942

Properties

Application: ELISA, WB
Antibody Type: Monoclonal
Clone: 13B20
Conjugate: No
Host: Mouse
Reactivity: Human, Monkey, Mouse
Immunogen: Purified recombinant fragment of human AKT1 expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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