Anti-AIMP1/EMAPII/SCYE1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A304-896A-T 20 µl (2 blots) -

6 - 10 business days*

131.00€
A304-896A-M 100 µl (10 blots) -

6 - 10 business days*

313.00€
A304-896A 100 µl (100 µg) -

6 - 10 business days*

465.00€
 
Protein function: Non-catalytic component of the multisynthase complex. Stimulates the catalytic... more
Product information "Anti-AIMP1/EMAPII/SCYE1"
Protein function: Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase (PubMed:10358004). Binds tRNA. Possesses inflammatory cytokine activity (PubMed:11306575). Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair (PubMed:16472771). Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations (PubMed:12237313). Induces maturation of dendritic cells and monocyte cell adhesion (PubMed:11818442). Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7 (PubMed:19362550). [The UniProt Consortium]
Keywords: Anti-EMAP2, Anti-AIMP1
Supplier: Bethyl Laboratories
Supplier-Nr: A304-896A

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse (Expected: Rabbit, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, White-tufted-ear Marmoset, Crab-eating Macaque, Northern White-cheeked Gibbon, Tasmanian Devil)
Immunogen: synthetic peptide. The epitope recognized by A304-896A-T maps to a region between residue 262 to 312 of human Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43) [Cleaved into: Endothelial monocyte-activating polypeptide 2 (EMAP-2) (Endothelial monocyte-activating polypeptide II) (EMAP-II) (Small inducible cytokine subfamily E member 1)] using the numbering given in entry Q12904 (GeneID 9255).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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