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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A304-895A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A304-895A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Non-catalytic component of the multisynthase complex. Stimulates the catalytic... more
Product information "Anti-AIMP1/EMAPII/SCYE1"
Protein function: Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase (PubMed:10358004). Binds tRNA. Possesses inflammatory cytokine activity (PubMed:11306575). Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair (PubMed:16472771). Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations (PubMed:12237313). Induces maturation of dendritic cells and monocyte cell adhesion (PubMed:11818442). Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7 (PubMed:19362550). [The UniProt Consortium]
Keywords: | Anti-EMAP2, Anti-AIMP1 |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A304-895A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse (Expected: horse, rabbit, orangutan, rhesus monkey, gorilla, chimpanzee, cat, african elephant, crab-eating macaque, brandt's bat, little brown bat, northern white-cheeked gibbon, small-eared galago, black flying fox) |
Immunogen: | synthetic peptide. The epitope recognized by A304-895A-T maps to a region between residue 125 to 175 of human Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43) [Cleaved into: Endothelial monocyte-activating polypeptide 2 (EMAP-2) (Endothelial monocyte-activating polypeptide II) (EMAP-II) (Small inducible cytokine subfamily E member 1)] using the numbering given in entry Q12904 (GeneID 9255). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K15437 | Matching products |
UniProt ID : | Q12904 | Matching products |
Gene ID | GeneID 9255 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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