Anti-ADRA1B

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-12279.20 20 µl -

7 - 16 business days*

71.00€
E-AB-12279.60 60 µl -

7 - 16 business days*

143.00€
E-AB-12279.120 120 µl -

7 - 16 business days*

238.00€
E-AB-12279.200 200 µl -

7 - 16 business days*

396.00€
 
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor... more
Product information "Anti-ADRA1B"
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. Protein function: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes. [The UniProt Consortium]
Keywords: Anti-ADRA1B, Anti-Alpha-1B adrenoceptor, Anti-Alpha-1B adrenoreceptor, Anti-Alpha-1B adrenergic receptor, ADRA1B Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-12279

Properties

Application: WB, IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Synthetic peptide of human ADRA1B
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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