Anti-4E-BP1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG65800.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Repressor of translation initiation that regulates EIF4E activity by preventing... more

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Product information "Anti-4E-BP1"

Protein function: Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. [The UniProt Consortium]

Keywords:	Anti-PHAS-I, Anti-4E-BP1, Anti-EIF4EBP1, Anti-eIF4E-binding protein 1, Anti-Eukaryotic translation initiation factor 4E-binding protein 1, Anti-Phosphorylated heat- and acid-stable protein regulated by insulin 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG65800

Properties

Application:	ICC, IF, IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat (Expected: bovine, swine, zebrafish)
Immunogen:	KLH-conjugated synthetic peptide around the N-terminus of Human 4E-BP1
MW:	12.5 kD
Format:	Antigen Affinity Purified