Anti-phospho-4E-BP1 (Thr45)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG51714.50	50 µl		-	-	6 - 14 business days*		436.00€
ARG51714.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Repressor of translation initiation that regulates EIF4E activity by preventing... more

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Product information "Anti-phospho-4E-BP1 (Thr45)"

Protein function: Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. [The UniProt Consortium]

Keywords:	Anti-phospho-PHAS-I, Anti-phospho-4E-BP1, Anti-phospho-EIF4EBP1, Anti-phospho-eIF4E-binding protein 1, Anti-phospho-Eukaryotic translation initiation factor 4E-binding protein 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG51714

Properties

Application:	WB, IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Peptide sequence around phosphorylation site of threonine 45 (S-T-T(p)-P-G) derived from Human 4E-BP1
Format:	Affinity Purified