Recombinant Human Semaphorin 5A / SEMA5A Protein (His tag)

Recombinant Human Semaphorin 5A / SEMA5A Protein (His tag)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-PKSH031161.50 50 µg -

7 - 16 business days*

869.00€
 
Protein function: Bifunctional axonal guidance cue regulated by sulfated proteoglycans,... more
Product information "Recombinant Human Semaphorin 5A / SEMA5A Protein (His tag)"
Protein function: Bifunctional axonal guidance cue regulated by sulfated proteoglycans, attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis. [The UniProt Consortium]
Supplier: Elabscience
Supplier-Nr: E-PKSH031161

Properties

Conjugate: No
Species reactivity: human
Format: Lyophilized

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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