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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
532351.10 | 10 µg | - | - |
3 - 19 business days* |
402.00€
|
||
532351.50 | 50 µg | - | - |
3 - 19 business days* |
837.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Neutrophil elastase, also known as polymorphonuclear leukocyte eslastase, is a serine protease... more
Product information "Neutrophil Elastase, Recombinant, Mouse, aa27-265, His-Tag"
Neutrophil elastase, also known as polymorphonuclear leukocyte eslastase, is a serine protease that classified as the chymotrypsin family. This protein breaks down elastin, an elastic fiber together with collagen and determines the mechanical properties of connective tissue. The neutrophil form breaks down the outer membrane protein A (OmpA) of E. coli and other Gram-negative bacteria. Also, this protein is inhibited by the acute-phase protein alpha 1-antitrypsin (A1AT), which binds almost irreversibly to the active site of elastase and trypsin. A1AT is normally secreted by the liver cells into the serum. Alpha-1-antitrypsin deficiency (A1AD) leads to uninhibited destruction of elastic fiber by elastase. Source: Recombinant protein corresponding to aa27-265 from mouse Neutrophil Elastase fused to His-Tag at C-terminal, expressed in Baculovirus. Molecular Weight: ~26.8kDa (245aa), Endotoxin: ~1EU/1ug (LAL), AA Sequence: SEIVGGRPAR PHAWPFMASL QRRGGHFCGA TLIARNFVMS AAHCVNGLNF RSVQVVLGAH DLRRQERTRQ TFSVQRIFEN GFDPSQLLND IVIIQLNGSA TINANVQVAQ LPAQGQGVGD RTPCLAMGWG RLGTNRPSPS VLQELNVTVV TNMCRRRVNV CTLVPRRQAG ICFGDSGGPL VCNNLVQGID SFIRGGCGSG LYPDAFAPVA EFADWINSII RSHNDHLLTH PKDREGRTNH HHHHH, Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | Ela2, Elane, Elastase-2, EC=3.4.21.37, Leukocyte elastase, Neutrophil elastase |
Supplier: | United States Biological |
Supplier-Nr: | 532351 |
Properties
Conjugate: | No |
Host: | Insect cells |
Species reactivity: | mouse |
MW: | 26.8 kD |
Purity: | >=90% (SDS-PAGE) |
Database Information
KEGG ID : | K01327 | Matching products |
UniProt ID : | Q3UP87 | Matching products |
Gene ID | GeneID 50701 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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