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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay11288-100 | 100 µg | - |
6 - 10 business days* |
481.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Key Features Cayman's CBP bromodomain TR-FRET Assay Kit (Cay-600850) was developed using... more
Product information "CREB-binding protein bromodomain (human recombinant)"
Key Features Cayman's CBP bromodomain TR-FRET Assay Kit (Cay-600850) was developed using CREB-binding protein bromodomain (human recombinant) protein.Bulk sizes available upon request The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. Acetylated lysine residues are recognized by a small protein domain known as a bromodomain. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as "readers" of histone acetylation marks regulating the transcription of target promoters. The cAMP response element-binding protein (CREB) binding protein (CREBBP) bromodomain has been shown to modulate the stability and function of the tumor suppressor protein p53. CREBBP bromodomain recognizes the acetylated lysine residue 382 on p53.{20307, 20273} This product contains the bromodomain region of CREBBP.Synonyms: cAMP-Response Element-binding Protein 1 CREB-1, CBP, CREBBP. Purity: >91% estimated by SDS-PAGE. Source: recombinant N-terminal GST-tagged protein expressed in E. coli. Amino Acids: 1081-1197. MW: 40.8 kDa. Storage Buffer: 50 mM Tris, pH 7.5, with 500 mM sodium chloride, 5% glycerol, and 5 mM beta-mercaptoethanol. UniProt Accession #: Q92793.
Keywords: | CBP, CREBBP, CREB-binding protein, CREB-binding protein, Histone lysine acetyltransferase CREBBP, Protein-lysine acetyltransferase CREBBP, Histone lysine acetyltransferase CREBBP, Protein-lysine acetyltransferase CREBBP |
Supplier: | Cayman Chemical |
Supplier-Nr: | 11288 |
Properties
Application: | Gene Regulation studies |
Conjugate: | No |
Host: | E.coli |
MW: | 40,8 kD |
Purity: | >91% estimated by SDS-PAGE |
Format: | Solution |
Database Information
KEGG ID : | K04498 | Matching products |
UniProt ID : | Q92793 | Matching products |
Gene ID | GeneID 1387 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -80°C (International: -80°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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