CA125 Cancer Antigen (Ovarian Cancer)

According to the ISOBM-TD-1 workshop, CA125 contains three antigenic domains: A-domain (Oc125), B-domain (M11), C-Domain (Ov197). The CA-125 antigen is present on a mucin-like glycoprotein of > 200kD and is detectable on the apical surface of normal endometrium and endocervix. Applications: Suitable for use Western Blot, Immunization and Labeling. Other applications have not been tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. May be stored at 4°C for 12 days with minimal activity loss.