Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
AG-40B-0192-C050 | 50 µg | - |
3 - 9 business days* |
440.00€
|
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AG-40B-0192-3050 | 150 µg (3 x 50 µg) | - |
3 - 9 business days* |
880.00€
|
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Extracellular domain of human ACE2 (aa 18-740) are fused at the C-terminus to a FLAG(R)-tag. Binds to the Spike protein of the coronavirus SARS-CoV-2. Protein function: Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator (PubMed:10969042, PubMed:10924499, PubMed:11815627). Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency (PubMed:11815627). By cleavage of angiotensin II, may be an important regulator of heart function (PubMed:10969042, PubMed:10924499). By cleavage of angiotensin II, may also have a protective role in acute lung injury. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SL6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity (PubMed:18424768, PubMed:19185582). [The UniProt Consortium]
Keywords: | ACE2, EC=3.4.17.23, SARS-Receptor, Angiotensin-converting Enzyme 2, ACEH, Metalloprotease MPROT15, SARS-CoV-2-Receptor |
Supplier: | AdipoGen Life Sciences |
Supplier-Nr: | AG-40B-0192 |
Properties
Application: | Binding assays |
Conjugate: | No |
Host: | Human cells |
Species reactivity: | human |
MW: | 110 kD |
Purity: | >=95% (SDS-PAGE) |
Format: | Lyophilized |
Database Information
KEGG ID : | K09708 | Matching products |
UniProt ID : | Q9BYF1 | Matching products |
Gene ID | GeneID 59272 | Matching products |
Handling & Safety
Storage: | -20°C (avoid repeat freezing and thawing cycles) |
Shipping: | +4°C (International: +4°C) |
Our products are for laboratory research use only: Not for administration to humans!