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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
544434.20 | 20 µg | - | - |
3 - 19 business days* |
493.00€
|
||
544434.100 | 100 µg | - | - |
3 - 19 business days* |
985.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
ACE2, also known as angiotensin-converting enzyme 2, is an integral membrane protein and a zinc... more
Product information "ACE2, Recombinant, Human, aa18-740, Fc-Tag"
ACE2, also known as angiotensin-converting enzyme 2, is an integral membrane protein and a zinc metalloprotease of the ACE family that also includes somatic and germinal ACE. ACE2 cleaves angiotensin 1 to angiotensin 1-9 and angiotensin 2 to angiotensin 1-7 as a carboxypeptidase. It may be an important regulator of heart function and have a protective role in acute lung injury. Partial recombinant protein corresponding to Gln18-Ser740 from human ACE2, fused to hFc-Tag at C-terminal, expressed in Mammalian cells. , Molecular Weight:, ~111.1kD, Biological Activity: 1. Measured by its binding ability in a functional ELISA. Immobilized SARS-CoV-2-S at 2ug/ml can bind human ACE2, the EC50 of human ACE2 protein is 56.64-103.6ng/ml, 2. Measured by its binding ability in a functional ELISA. Immobilized SARS-CoV-2-S1-RBD at 5ug/ml can bind human ACE2, the EC50 of human ACE2 protein is 31.80-44.69ng/ml. , 3. Measured by its binding ability in a functional ELISA. Immobilized SARS-CoV-2-S1-RBD at 5ug/ml can bind human ACE2, the EC50 of human ACE2 protein is 115.0-274.9ng/ml., 4. Measured by its binding ability in a functional ELISA. Immobilized human ACE2 at 2ug/ml can bind SARS-CoV-2-S1-RBD, the EC50 of human ACE2 protein is 8.363-12.82ng/ml., 5. SARS-CoV-2 Spike protein RBD his/myc tag captured on COOH chip can bind 544434 with an affinity constant of 13.8pM as detected by LSPR Assay. AA Sequence: QSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYADQSIKVRISLKSALGDKAYEWNDNEMYLFRSSVAYAMRQYFLKVKNQMILFGEEDVRVANLKPRISFNFFVTAPKNVSDIIPRTEVEKAIRMSRSRINDAFRLNDNSLEFLGIQPTLGPPNQPPVS, Storage and Stability: Lyophilized and reconstituted products may be stored at -20°C. Stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: | United States Biological |
Supplier-Nr: | 544434 |
Properties
Conjugate: | No |
Host: | Mammalian cells |
Species reactivity: | human |
MW: | 111.1 kD |
Purity: | >=85% (SDS-PAGE). |
Format: | Lyophilized |
Database Information
KEGG ID : | K09708 | Matching products |
UniProt ID : | Q9BYF1 | Matching products |
Gene ID | GeneID 59272 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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COVID-19 Research
COVID-19 Research
COVID-19 Research
COVID-19 Research
COVID-19 Research
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