Other Peptides

Sulfo-SMCC is a water-soluble protein cross-linking reagent that contains an anime-reactive sulfo-N-hydroxysuccinimide (sulfo-NHS) ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. It has been used to conjugate anti-programmed cell death ligand 1 (PD-L1) antibodies to...

[Ala1,3,11,15]-Endothelin-1 is an endothelin receptor type B (ETB) agonist and linear synthetic peptide derivative of endothelin-1 in which all four cysteine residues have been substituted with alanine. It selectively binds to ETB over ETA receptors (IC50s = 0.33 and 570 nM, respectively, for the porcine receptors)....

[Asp371]-Tyrosinase (369-377) is a naturally occurring tyrosinase antigen peptide. It is formed via post-translational modification of Asn371. [Asp371]-Tyrosinase (369-377) binds to MHC class I subtype HLA-A*0201-positive T2 cells (IC50 = 1.2 µg/ml) and induces lysis of HLA-A2.1-positive T2 cells incubated with...

MDM2 (32-46) is a peptide fragment of MDM2. Formal Name: ((S)-2-formylpyrrolidin-1-yl)-L-leucyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-lysyl-L-seryl-L-valylglycyl-L-alanyl-L-glutaminyl-L-lysyl-L-aspartic acid, trifluoroacetate salt. Molecular Formula: C75H135N19O20  XCF3COOH. Formula Weight: 1623.0. Purity:...

Semaglutide is an agonist of glucagon-like peptide 1 receptor (GLP-1R, EC50 = 6.2 pM in a reporter assay using BHK cells expressing the human receptor). It decreases blood glucose levels in the db/db mouse model of type 2 diabetes (ED50 = 98%. Formulation: (Request formulation change), A solid. Solubility: Methanol:...

Gonadorelin is a tropic hormone and agonist of the gonadotropin-releasing hormone receptor (GNRHR, Ki = 13 nM in CHO cells expressing the human receptor). It stimulates luteinizing hormone (LH) and follicle-stimulating hormone (FSH) release from rat anterior pituitary cultures when administered at a dose of 0.1 µg....

A thymic peptide hormone that induces the formation of E rosettes.

Microcystin-LR is a cyanotoxin and an inhibitor of protein phosphatase 2A (PP2A, Ki = 9 pM). It selectively inhibits PP2A over PP1C and PP1gamma (Kis = 180 and 240 pM, respectively). Intratracheal administration of microcystin-LR (100 µg/kg) induces hepatic bleeding in mice. Microcystin-LR has been found in...

Acetyl tetrapeptide-3 is a biomimetic peptide. It increases protein levels of type III collagen and total laminins in MRC5 human fibroblasts when used at a concentration of 1 µM. Acetyl tetrapeptide-3 reverses corticoid-induced decreases in collagen VII expression at the dermal-epidermal junction in human skin...

Myristoyl pentapeptide-17 is a myristoylated form of the pentapeptide Lys-Leu-Ala-Lys-Lys-NH2. It is active against E. coli (MIC = 10 ppm).Formal Name: N2-(1-oxotetradecyl)-L-lysyl-L-leucyl-L-alanyl-L-lysyl-L-lysinamide, acetate. Synonyms: Myr-KLAKK-NH2, Myr-KLAKK-amide, Myr-Lys-Leu-Ala-Lys-Lys-NH2. Molecular...

Carbetocin is an oxytocin receptor agonist and a peptide analog of oxytocin (Cay-11799). It selectively binds to oxytocin receptors over vasopressin V2 receptors (Kds = 1.96 and 61.3 nM, respectively). Carbetocin induces contraction of isolated rat uterine strips (EC50 = 48 nM) and inhibits oxytocin-induced...