Other Peptides

3,3',5'-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRalpha and TRbeta than 3,3',5-triiodo-L-thyronine (Cay-16028) and commonly described as inactive. However, high...

Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two...

Glucagon is a peptide hormone produced from proglucagon in pancreatic alpha cells that has a role in the regulation of glucose metabolism. Pulsatile application of glucagon to rat hepatocytes stimulates glucose production ex vivo. It also stimulates glucose output from perfused rat livers via increases in...

Tentoxin is a cyclic tetrapeptide first isolated from the plant pathogen A. alternata. It is an herbicide that inhibits chloroplast development, resulting in chlorotic tissue. Tentoxin is selectively phytotoxic, as it kills a number of important weeds at concentrations that have no effects on several important...

L-Leucyl-L-Leucine methyl ester (LLME) is a lysosomal condensation product that has been reported to be cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes without affecting helper T cells and B cells. It has also been shown to induce death of monocytes, polymorphonuclear leukocytes, and myeloid...

alpha-MSH (11-13) is a peptide fragment of alpha-melanocyte-stimulating hormone (alpha-MSH, Item No. 29923), a neuropeptide with anti-inflammatory and immunomodulatory activity. It is bactericidal against methicillin-resistant S. aureus (MRSA) with ~10% survival when used at a concentration of 1 µM. alpha-MSH...

Xenin-25 is an endogenous peptide and a neurotensin (NTS) receptor ligand. It binds to NTS receptors in HEK293 cell membranes expressing the mouse receptor. It is expressed in K cells in the small intestine and co-secreted with glucose-dependent insulinotropic polypeptide (GIP). Xenin-25 (1 µM) stimulates the...

H-L-Cys(MDNPE)-OH is a photocleavable derivative of the amino acid L-cysteine (Cay33309). Upon irradiation at 365 nm, L-cysteine is released. H-L-Cys(MDNPE)-OH has been used for site-specific caged cysteine incorporation in proteins in E. coli and HEK293T cells.. SMILES:...

H-Ala-Glu-Asp-OH (AED) is a synthetic tripeptide with geroprotective effects in vitro. It increases proliferation and reduces apoptosis in young and aged rat skin fibroblast cultures but reduces matrix metalloproteinase-9 (MMP-9) levels only in young cultures. AED (20 ng/ml) increases sirtuin 1 (SIRT1), SIRT6, and...

LDV-K(azide) is a functionalized peptide containing an LDV motif for binding integrin alpha4beta1 and a modified version of LDV-azide. LDV-K(azide) can be conjugated to alkyne-containing molecules via click chemistry.. SMILES:...

DC-2 peptide is a synthetic peptide that contains a DHHC palmitoylation motif. It reduces H-Ras cell membrane localization in HeLa cells and increases ERK and Akt phosphorylation in SW480 colorectal cancer cells with high EGFR expression but not in SW620 colorectal cancer cells with low EGFR expression. DC-2 reduces...

TX0121 is a peptide corresponding to amino acids 201-209 of centromere protein I (CENP-1).. SMILES:...