Blocking Peptides

Peptide is used to block TCF1 (C63D9) Rabbit mAb reactivity in immunohistochemistry protocols. LEF1 and TCF are members of the high mobility group (HMG) DNA binding protein family of transcription factors which consists of the following: Lymphoid enhancer factor 1 (LEF1), T Cell Factor 1 (TCF1), TCF3 and TCF4 (1)....

Peptide is used to block Thioredoxin 1 Rabbit mAb reactivity in immunohistochemistry protocols. Thioredoxin is a small redox protein found in many eukaryotes and prokaryotes. A pair of cysteines within a highly conserved, active site sequence can be oxidized to form a disulfide bond which is then reduced by...

Peptide is used to block TRAF1 Rabbit mAb reactivity in immunohistochemistry protocols. TRAFs (TNF receptor-associated factors) are a family of multifunctional adaptor proteins that bind to surface receptors and recruit additional proteins to form multiprotein signaling complexes capable of promoting cellular...

Peptide corresponding to amino acid 261 to 277 of human TRAIL., Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing...

Control peptide for W1002-70B only.

Peptide corresponding to amino acids 279 to 298 of human origin. Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis...

Control peptide for N5378-08D (antiserum) and N5378-08K (affinity purified antibody). Synthetic peptide corresponding to 16aa sequence near the C-terminus of human mature alpha defensin-6. Sequence is specific for human alpha defensin-6. No significant homology exists with other alpha-defensins. , Defensins are a...

Control Peptide for 036320. Protein function: Receptor for gastrin-releasing peptide (GRP) (PubMed:1655761). Signals via association with G proteins that activate a phosphatidylinositol-calcium second messenger system, resulting in Akt phosphorylation. Contributes to the regulation of food intake. Contributes to the...

ANPB (natriuretic peptide receptor B) is one of two integral membrane receptors for natriuretic peptides. Both ANPA and ANPB contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain), an helical hinge region...

CART has been found to control satiety modulating the actions of two key regulators of food intake, leptin and NPY. Starvation decreases CART levels in the arcuate nucleus (3). Obese animals have virtually no CART. CART inhibits both normal and starvation-induced feeding, and completely inhibits NPY-induced feeding....

CART has been found to control satiety modulating the actions of two key regulators of food intake, leptin and NPY. Starvation decreases CART levels in the arcuate nucleus (3). Obese animals have virtually no CART. CART inhibits both normal and starvation-induced feeding, and completely inhibits NPY-induced feeding....