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NEW
Item number: Cay39017-1
[Ala1,3,11,15]-Endothelin-1 is an endothelin receptor type B (ETB) agonist and linear synthetic peptide derivative of endothelin-1 in which all four cysteine residues have been substituted with alanine. It selectively binds to ETB over ETA receptors (IC50s = 0.33 and 570 nM, respectively, for the porcine receptors)....
Keywords: | [Ala1,3,11,15]-ET-1, 4-Ala-ET-1,... |
Application: | ETB receptor agonist |
MW: | 2367.7 D |
From 53.00€
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NEW
Item number: Cay39722-10
Aureobasidin A is a cyclic depsipeptide that has been found in A. pullulans and has diverse biological activities. It inhibits inositol phosphorylceramide synthase, an enzyme involved in sphingolipid biosynthesis (Kis = 0.18 and 0.23 for the C. albicans and S. cerevisiae enzymes, respectively). Aureobasidin A also...
Keywords: | Antibiotic R 106I, Basifungin, LY295337, NK 204, R 106-1,... |
Application: | Bioactive cyclic depsipeptide |
CAS | 127785-64-2 |
MW: | 1101.4 D |
From 218.00€
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NEW
Item number: Cay39747-1
Retatrutide is a triple agonist of the glucagon receptor (GCGR), glucagon-like peptide 1 receptor (GLP-1R), and gastric inhibitory polypeptide receptor (GIP receptor), also known as the glucose-dependent insulinotropic polypeptide receptor. It induces cAMP accumulation in HEK293 cells expressing the human GCGR,...
Keywords: | LY3437943,... |
Application: | GCGR / GLP-1R / GIPR triple agonist |
MW: | 4731.3 D |
From 77.00€
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NEW
Item number: Cay39986-1
PE 22-28 is a peptide inhibitor of the two-pore domain potassium channel K2P2.1/TREK1 (IC50 = 0.1 nM in HEK293 cells expressing the human channel) and a fragment of spadin (Cay-36762). It is selective for K2P2.1/TREK1 over K2P10.1 /TREK2, K2P13.1/TRAAK, K2P18.1/TRESK, and K2P3.1/TASK1 in HEK293 cells expressing the...
Keywords: | Gly-Val-Ser-Trp-Gly-Leu-Arg-OH, glycyl-L-valyl-L-seryl-L-tryptophylglycyl-L-leucyl-L-arginine, acetate |
Application: | K2P2.1/TREK1 peptide inhibitor |
MW: | 773.9 D |
From 119.00€
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NEW
Item number: Cay40152-1
[Asp371]-Tyrosinase (369-377) is a naturally occurring tyrosinase antigen peptide. It is formed via post-translational modification of Asn371. [Asp371]-Tyrosinase (369-377) binds to MHC class I subtype HLA-A*0201-positive T2 cells (IC50 = 1.2 µg/ml) and induces lysis of HLA-A2.1-positive T2 cells incubated with...
Keywords: | [Asp370]-Tyrosinase (368-376), Tyr-Met-Asp-Gly-Thr-Met-Ser-Gln-Val,... |
Application: | Tyrosinase antigen peptide |
MW: | 1031.2 D |
From 34.00€
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NEW
Item number: Cay38836-1
MDM2 (32-46) is a peptide fragment of MDM2. Formal Name: ((S)-2-formylpyrrolidin-1-yl)-L-leucyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-lysyl-L-seryl-L-valylglycyl-L-alanyl-L-glutaminyl-L-lysyl-L-aspartic acid, trifluoroacetate salt. Molecular Formula: C75H135N19O20 XCF3COOH. Formula Weight: 1623.0. Purity:...
Keywords: | ((S)-2-formylpyrrolidin-1-yl)-L-leucyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-lysyl-L-seryl-L-valylglycyl-L-alanyl-... |
MW: | 1623 D |
From 36.00€
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NEW
Item number: Cay40298-1
[Gly8,36,Glu22]-Glucagon-like peptide 1 ([Gly8,36,Glu22]-GLP-1) (7-37) is a derivative of GLP-1 containing alanine-to-glycine, glycine-to-glutamate, and arginine-to-glycine substitutions at positions 8, 22, and 36, respectively, and a peptide fragment of the GLP-1 receptor (GLP-1R) agonist dulaglutide.Formal Name:...
Keywords: | [Gly8,36,Glu22]-Glucagon-like Peptide 1 (7-37),... |
Application: | Dulaglutide fragment, GLP-1 derivative |
MW: | 3314.6 D |
From 47.00€
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NEW
Item number: Cay40868-1
Mechercharmycin A is a cyclic peptide originally isolated from Thermoactinomyces that has anticancer activity. It induces cytotoxicity in A549 lung cancer and Jurkat leukemia cells (IC50s = 40 and 46 nM, respectively).Formal Name:...
Keywords: | IB-01211,... |
Application: | Cyclic peptide, anticancer agent |
CAS | 822520-96-7 |
MW: | 708.7 D |
784.00€
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Item number: BOT-10402
NucView(R) 488 Caspase-3 Substrate is a novel cell membrane-permeable fluorogenic caspase substrate designed for detecting caspase-3/7 activity within live cells in real time. Unlike conventional caspase assays, NucView(R) 488 Caspase-3 Substrate detects caspase-3/7 activity within individual intact cells without...
From 111.00€
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Item number: BOT-10403
NucView(R) 488 Caspase-3 Substrate is a novel fluorogenic caspase substrate for real-time detection of caspase-3/7 activity in live cells. In apoptotic cells, the substrate is cleaved to release a DNA dye that stains the nucleus with bright green fluorescence. 1 mM in PBS, 100 uL.
From 111.00€
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Item number: BOT-10404
Ac-DEVD-CHO is a synthetic tetrapeptide competitive inhibitor for Caspase-3/7, and contains the amino acid sequence of the PARP cleavage site. Ac-DEVD-CHO can be used to inhibit Caspase-3/7 activity in apoptotic cells, and to study events downstream of Caspase-3/7 activation.Soluble in DMSOStore at 4°CC20H30N4O11MW:...
From 121.00€
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Item number: BOT-10405
NucView(R) 405 Caspase-3 Substrate, 1 mM in DMSO, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry. In contrast to other fluorogenic caspase substrates or fluorescent caspase inhibitor based (FLICA) assays, NucView(R)...
From 111.00€
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