Peptides

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Glepaglutide (acetate)
Glepaglutide (acetate)

Item number: Cay41274-1

Glepaglutide is a peptide agonist of the glucagon-like peptide 2 receptor (GLP-2R). It selectively induces cAMP accumulation in HEK293 cells expressing GLP-2R over those expressing GLP-1R (EC50s = 0.24 and 8.7 nM, respectively, for the human receptors). Glepaglutide (10 mg/kg per day for 26 weeks) increases mucosal...
Keywords: ZP1848
Application: Peptide, GLP-2R agonist
MW: 4316.1 D
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Utreglutide
Utreglutide

Item number: Cay41275-1

Utreglutide is a G protein-biased peptide agonist of glucagon-like peptide 1 receptor (GLP-1R). It selectively induces cAMP accumulation in HEK293 cells expressing human GLP-1R over beta-arrestin recruitment in CHO-K1 cells expressing human GLP-1R (EC50s = 0.63 and 79 nM, respectively). Utreglutide induces insulin...
Keywords: GL0034,...
Application: G-protein-biased peptide GLP-1R agonist
CAS 2460862-12-6
MW: 4166.7 D
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HOXB7 (8-25) (human)
HOXB7 (8-25) (human)

Item number: Cay41334-1

HOXB7 (8-25) is a peptide fragment of the transcription factor homeobox protein B7 (HOXB7).Formal Name:...
Keywords: Homeobox Protein B7 (8-25),...
Application: HOXB7 peptide fragment
MW: 1848 D
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Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH
Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH

Item number: Cay40707-1

Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH is a building block in the synthesis of the glucagon-like peptide 1 receptor (GLP-1R) agonist semaglutide (Cay-40231, Cay-29969, Cay-40170).Formal Name:...
Keywords: Fmoc-Lys(tBuOCO-(CH2)16-CO-Glu(AEEA-AEEA)-OtBu)-OH,...
Application: Semaglutide synthesis building block
CAS 1662688-20-1
MW: 1196.5 D
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Cotadutide (acetate)
Cotadutide (acetate)

Item number: Cay40714-1

Cotadutide is a synthetic peptide and dual agonist of the glucagon-like peptide 1 receptor (GLP-1R) and glucagon receptor (GCGR) that is biased toward GLP-1R. It increases cAMP accumulation in CHO cells overexpressing recombinant human GLP-1R or GCGR (EC50s = 6.9 and 10.2 pM, respectively). It also enhances...
Keywords: MEDI0382
Application: GLP-1R / GCGR dual agonist, synthetic peptide
MW: 3788.1 D
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Fexapotide (trifluoroacetate)
Fexapotide (trifluoroacetate)

Item number: Cay40716-10

Fexapotide (trifluoroacetate) is a peptide. It induces apoptosis in LNCaP prostate cancer cells when used at a concentration of 2.5 mg/ml. Intraprostatic administration of fexapotide triflutate (0.6 mg/animal per week) reduces the numbers of prostate glandular epithelial cells without affecting other cell types and...
Keywords: NX-1207,...
Application: Antineoplastic, proapoptotic peptide
CAS 1609252-56-3
MW: 2625.6 D
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GLP-1 (1-32) (bullfrog) (trifluoroacetate salt)
GLP-1 (1-32) (bullfrog) (trifluoroacetate salt)

Item number: Cay40718-1

Glucagon-like peptide 1 (GLP-1) (1-32) is an endogenous incretin hormone. It increases intracellular cAMP levels using HEK293 cells expressing human GLP-1 receptor (GLP-1R, EC50 = 0.051 nM). In vivo, GLP-1 (1-32) (30 mg/kg) reduces blood glucose levels in an oral glucose tolerance test (OGTT) in fasted mice.Formal...
Keywords: Glucagon-like Peptide 1 (1-32),...
Application: Endogenous incretin hormone
MW: 3658.1 D
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Semaglutide Side Chain
Semaglutide Side Chain

Item number: Cay40746-1

Semaglutide side chain is a synthetic intermediate. It has been used as an intermediate in the synthesis of the glucagon-like peptide 1 receptor (GLP-1R) agonist semaglutide (Cay-40231, Cay-29969, Cay-40170), as well as a lipid side chain to increase the proteolysis-resistance of insulin derivatives for use in...
Keywords: 22S-[(1,1-dimethylethoxy)carbonyl]-10,19,24-trioxo-3,6,12,15-Tetraoxa-9,18,23-triazahentetracontanedioic acid,...
Application: Synthetic intermediate
CAS 1118767-16-0
MW: 846.1 D
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(BOC-VPR)2R110
(BOC-VPR)2R110

Item number: ABD-13462

(BOC-VPR)2R110 is a sentive fluorogenic substrate for alpha-thrombin. The non-fluorescent substrate generates a bright green fluorescent R110 product that has Ex/Em = 495/520 nm, and can be easily detected with the FITC filter set. This substrate has also been used for the rapid detection of MRSA...
Application: Fluorogenic alpha-thrombin substrate
139.00€ *
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L-Leucyl-L-Leucine methyl ester (hydrochloride)
L-Leucyl-L-Leucine methyl ester (hydrochloride)

Item number: Cay16008-100

L-Leucyl-L-Leucine methyl ester (LLME) is a lysosomal condensation product that has been reported to be cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes without affecting helper T cells and B cells. It has also been shown to induce death of monocytes, polymorphonuclear leukocytes, and myeloid...
Keywords: LLME, LLOMe, L-leucyl-L-leucine, methyl ester, monohydrochloride
Application: Specific cytotoxin
CAS 6491-83-4
MW: 294.8 D
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MDM2 (32-46) (trifluoroacetate salt)
MDM2 (32-46) (trifluoroacetate salt)

Item number: Cay38836-1

MDM2 (32-46) is a peptide fragment of MDM2. Formal Name: ((S)-2-formylpyrrolidin-1-yl)-L-leucyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-lysyl-L-seryl-L-valylglycyl-L-alanyl-L-glutaminyl-L-lysyl-L-aspartic acid, trifluoroacetate salt. Molecular Formula: C75H135N19O20  XCF3COOH. Formula Weight: 1623.0. Purity:...
Keywords: ((S)-2-formylpyrrolidin-1-yl)-L-leucyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-lysyl-L-seryl-L-valylglycyl-L-alanyl-...
MW: 1623 D
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HBP08 (trifluoroacetate salt)
HBP08 (trifluoroacetate salt)

Item number: Cay36961-1

HBP08 is a peptide inhibitor of the protein-protein interaction between chemokine (C-X-C motif) ligand 12 (CXCL12) and high mobility group protein B1 (HMGB1). It binds to HMGB1 (Kd = 0.8 µM) and inhibits HMGB1-induced inhibition of CXCL12-induced migration of 300-19 pre-B cells expressing human chemokine (C-X-C...
Keywords: glycyl-L-tyrosyl-L-histidyl-L-tyrosyl-L-alpha-glutamyl-L-arginyl-L-tryptophyl-L-isoleucyl-L-histidine, trifluoroacetate salt
Application: CXCL12-HMGB1 protein-protein interaction peptide inhibitor
MW: 1260.4 D
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2 from 998 pages