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Peptide P60
Item number: TGM-TP3042-10mg
Description: Peptide P60 acts as a FOXP3 inhibitor. This compound can penetrate cells to hinder FOXP3's nuclear translocation and diminish its ability to suppress transcription factors NF-kappaB and NFAT. Peptide P60 also suppresses the immunosuppressive activity of regulatory T cells (Treg) derived from mice and...
| Keywords: | Peptide P60 , FOXP3 inhibitor P60 |
| MW: | 1994.34 D |
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mcK6A1
Item number: TGM-TP3044-10mg
Description: mcK6A1 serves as an inhibitor of amyloid-beta (Abeta) aggregation, selectively binding to the 16KLVFFA21 fragment of Abeta42, leading to the formation of an extended beta-sheet structure and preventing the formation of Abeta42 oligomers. This compound is valuable for research into Alzheimer's disease...
| MW: | 1446.65 D |
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QPH-FR
Item number: TGM-TP3080-10mg
Description: QPH-FR is a quinoa peptide and acts as an inhibitor of the G protein-coupled receptor 5 (LGR5) that is abundant in leucine repeat sequences. By binding to LGR5, QPH-FR competitively inhibits the formation of the LGR5/RSPO1 complex. This interaction leads to the ubiquitination of FZD receptors by...
| MW: | 1862.01 D |
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CT-08
Item number: TGM-TP3082-10mg
Description: CT-08 (CT8, Compound 3) is a macrolide Sec61 modulator that inhibits protein secretion in a signal sequence-dependent manner. It prevents the Sec61-mediated translocation of VCAMss-GLuc to the ER, resulting in the loss of luciferase activity. Additionally, CT-08 suppresses the expression of VCAM in...
| MW: | 893.206 D |
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PL120131
Item number: TGM-TP3086-10mg
Description: PL120131 is a PD-1/PD-L1 inhibitory peptide that disrupts the interaction between PD-1 and PD-L1 by binding to PD-1. This compound can inhibit the apoptosis signaling pathway mediated by PD-1, thereby preventing apoptosis (apoptosis) in Jurkat cells and primary lymphocytes. Additionally, PL120131...
| MW: | 1404.61 D |
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AT1R epitope
Item number: TGM-TP3088-10mg
Description: AT1R epitope (iCF10) is a heptapeptide and acts as a competitive inhibitor of cCF10, a peptide pheromone. Target: Endogenous Metabolite. Smiles: [C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](C)N)=O)[C@H](CC)C)=O)[C@@H](C)O)=O)CC(C)C)=O)[C@H](CC)C)=O)C(N[C@@H]([C@H](CC)C)C(O)=O)=O
| MW: | 790.002 D |
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QMT-CBT
Item number: TGM-TP3089-10mg
Description: QMT-CBT is a near-infrared aggregation-induced emission compound. Upon activation of caspase1 (Cas1), QMT-CBT undergoes a CBT-Cys click reaction, forming a cyclic dimer known as QMT-Dimer (the first aggregate), which further assembles into nanoparticles (the second aggregate). This process turns on the...
| MW: | 1805.09 D |
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BCY8234
Item number: TGM-TP3094-10mg
Description: BCY8234 is an analogue of BT8009 that does not contain MMAE. BT8009 is a toxin conjugate targeting nectin-4, utilized in the treatment of solid tumors. BCY8234 can reduce the response to BT8009. Smiles:...
| MW: | 2954.34 D |
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Lutetate tezuvotide tetraxetan
Item number: TGM-TP3095-10mg
Description: Lutetate tezuvotide tetraxetan is the tetrahydrogenated form of Tetraxetan, which is also known as DOTA, a chelating agent employed in the synthesis of contrast agents for oncological medicine. Smiles:...
| MW: | 1571.49 D |
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RI-OR2
Item number: TGM-TP3103-10mg
Description: RI-OR2 is a retro-inverso peptide that acts as an amyloid-beta (Abeta) oligomerization inhibitor. It binds to fixed beta-Amyloid (1-42) monomers and fibrils, with an apparent Kd of 9-12 µM, and also serves as an inhibitor of Abeta(1-42) fibril extension. Target: Beta Amyloid. Smiles:...
| MW: | 1120.35 D |
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GRF (1-29) amide (rat)
Item number: TGM-TP3111-10mg
Description: GRF (1-29) amide (rat) is a synthetic peptide that stimulates the secretion of growth hormone (GH). Target: Others. Smiles:...
| Keywords: | rGHRH(1-29)NH2 , GRF (1-29) amide (rat) |
| MW: | 3473.02 D |
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H-20
Item number: TGM-TP3114-10mg
Description: H-20 is a PD-1 agonist that reduces the required dosage of morphine for analgesia. It can be used in studies related to chronic pain. Target: PD-1/PD-L1. Smiles:...
| MW: | 973.037 D |
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