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Product information "Tumor Necrosis Factor Receptor, mouse recombinant (rmTNF-R1)"
Protein function: Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate- specific cysteine proteases) mediating apoptosis. [The UniProt Consortium]
Keywords:
p55, p60, TNF-R1, TNFR-I, Tnfr-1, TNF-RI, CD120a, Tnfrsf1a, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor type I, Tumor necrosis factor receptor superfamily member 1A
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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