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Viewed
Protein function: Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate- specific cysteine proteases) mediating apoptosis. [The UniProt Consortium]
Keywords: | p55, p60, TNF-R1, TNFR-I, Tnfr-1, TNF-RI, CD120a, Tnfrsf1a, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor type I, Tumor necrosis factor receptor superfamily member 1A |
Supplier: | Biomol GmbH |
Supplier-Nr: | 99937.1 |
Properties
Application: | Cell culture |
Conjugate: | No |
Expressed in: | E.coli |
Origin: | Mouse |
MW: | 21,1 kD |
Purity: | >97% |
Database Information
KEGG ID : | K03158 | Find alternatives |
UniProt ID : | P25118 | Find alternatives |
Gene ID | GeneID 21937 | Find alternatives |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |