Interleukin-9/IL-9/Cytokine P40 Protein(C-6His) (recombinant human)

Activity: Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cellsThe ED50 for this effect is typically Less than 0.5 ng/ml Protein Construction: Recombinant Human Interleukin-9 is produced by our Mammalian expression system and the target gene encoding Glu19-Ile144 is expressed with a 6His tag at the C-terminus. Sequence: Glu19-Ile144. Fusion tag: C-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 37 kDa. Protein function: Interleukin-9 (IL-9) is a secreted protein that belongs to the IL-7/IL-9 family. IL-9 supports IL-2 independent and IL-4 independent growth of helper T-cells. IL-9 stimulates cell proliferation and prevents apoptosis. It functions through the IL-9 receptor (IL-9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. IL-9 has been identified as a candidate gene for asthma. IL-9 is a determining factor in the pathogenesis of bronchial hyperresponsiveness. Protein function: Supports IL-2 independent and IL-4 independent growth of helper T-cells. [The UniProt Consortium]