Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
97634.2 | 2 µg | - | - |
3 - 10 business days* |
94.00€
|
||
97634.10 | 10 µg | - | - |
3 - 10 business days* |
208.00€
|
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IL-7 human recombinant produced in HEK cells is a glycosylated monomer, having a molecular weight range of 19-30 kDa due to glycosylation. IL-7 is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. The biological activity was determined by the dose dependent stimulation of the proliferation of murine 2E8 cells and is typically 0.6 ng/ml corresponding to a specific activity of 1,666,667 units/mg.
Keywords: | Lymphopoietin 1 (LP-1), pre-B cell factor, IL-7 |
Supplier: | Biomol GmbH |
Supplier-Nr: | 97634 |
Properties
Application: | Cell culture |
Conjugate: | No |
Host: | Human cells |
Species reactivity: | human |
Purity: | >95% |
Format: | Lyophilized |
Database Information
KEGG ID : | K05431 | Matching products |
UniProt ID : | P13232 | Matching products |
Gene ID | GeneID 3574 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Our products are for laboratory research use only: Not for administration to humans!