IL17B, Recombinant, Human, aa21-180, His-Tag (Interleukin-17B, Interleukin-17B Isoform 1, IL-17B, IL

IL17B, also known as interleukin-17B isoform 1, is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. It plays a role in inflammation and bone growth. IL-17B binds to IL-17 RB and induces the production of inflammatory cytokines and the infiltration of inflammatory immune cells. Source: Recombinant protein corresponding to aa21-180 from human IL17B, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~19.2kD (169aa), 18-28kD (SDS-PAGE under reducing conditions.), Endotoxin: <1EU/1ug (determined by LAL method), AA Sequence: ADPQPRSPKS KRKGQGRPGP LAPGPHQVPL DLVSRMKPYA RMEEYERNIE EMVAQLRNSS ELAQRKCEVN LQLWMSNKRS LSPWGYSINH DPSRIPVDLP EARCLCLGCV NPFTMQEDRS MVSVPVFSQV PVRRRLCPPP PRTGPCRQRA VMETIAVGCT CIFHHHHHH, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.