IL-6, chicken recombinant (rchIL-6)

Item number	Size	Manual	SDS	Delivery time	Price
RP0299C-005	5 µg	-		3 - 8 business days*	206.00€
RP0299C-025	25 µg	-	-	3 - 8 business days*	412.00€
RP0299C-100	100 µg	-		3 - 8 business days*	1,235.00€
RP0299C-500	500 µg	-		3 - 8 business days*	4,528.00€

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Produced in Yeast. Amino acid sequence: VPLPAAADSS GEVGLEEEAG ARRALLDCEP LARVLRDRAV QLQDEMCKKF... more

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Product information "IL-6, chicken recombinant (rchIL-6)"

Produced in Yeast. Amino acid sequence: VPLPAAADSS GEVGLEEEAG ARRALLDCEP LARVLRDRAV QLQDEMCKKF TVCENSMEML VRNNLNLPKV TEEDGCLLAG FDEEKCLTKL SSGLFAFQTY LEFIQETFDS EKQNVESLCY STKHLAATIR QMVINPDEVV IPDSAAQKSL LANLKSDKDW IEKITMHLIL RDFTSFMEKT VRAVRYLKKT RSFSA (195). Protein function: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane- bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells. [The UniProt Consortium]