Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
F4210-10C.2 | 2 µg | - | - |
3 - 19 business days* |
598.00€
|
||
F4210-10C.10 | 10 µg | - | - |
3 - 19 business days* |
757.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Single-chain polypeptide growth factor that plays a significant role in the process of wound... more
Product information "Fibroblast Growth Factor Acidic (FGFa), human recombinant (rHuFGFa)"
Single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of angiogenesis. It binds to heparin, which potentiates its biological activity and protects it from proteolysis. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages, and also has chemotactic and mitogenic activities. It was originally named acidic fibroblast growth factor based upon its chemical properties and to distinguish it from basic fibroblast growth factor. , Other homologous FGF belonging to the same family are int-2 (FGF-3 ), FGF-5 , FGF-6 , K-FGF and KGF (keratinocyte growth factor =FGF-7 ). All factors are products of different genes, some of which are Oncogene products (FGF-3 , FGF-4 , FGF-5 ). , Recombinant Human FGF-a (FGF-1) produced in Sf9 insect cells is a single, glycosylated, polypeptide chain containing 140 amino acids and having a molecular mass of 15803 Dalton. , Recombinant Human FGF-a is purified by proprietary chromatographic techniques. Amino acid sequence: The sequence of the first five N-terminal amino acids was determined and was found to be Met-Phe-Asn-Leu-Pro. Dimers and aggregates: < 1% as determined by silver-stained SDS-PAGE gel analysis. Biological Activity: Recombinant Human FGF-a is fully biologically active when compared to standards. The ED50, calculated by the dose-dependent proliferation of BAF3 cells expressing FGF receptors (measured by 3H-thymidine uptake) is <10ng/ml, corresponding to a specific activity of 105Units/mg. Endotoxin: < 0.1ng/ug (IEU/ug) of FGF-acidic-Sf9. Protein content: Protein quantitation was carried out by two independent methods: , 1. UV spectroscopy at 280 nm. , 2. Analysis by RP-HPLC, using a calibrated solution of FGF-a as a Reference Standard. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: | United States Biological |
Supplier-Nr: | F4210-10C |
Properties
Conjugate: | No |
Host: | Insect cells |
Species reactivity: | human |
Format: | Highly Purified |
Database Information
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed