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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Human recombinant FGF-23 C-term protein is 8.67 kDa protein containing 72 amino acid residues and... more
Product information "Fibroblast Growth Factor-23 C-Terminal, His Tag, human recombinant (rHuFGF23-N-His)"
Human recombinant FGF-23 C-term protein is 8.67 kDa protein containing 72 amino acid residues and an additional 9 amino acids His-Tag at N-terminus. FGF-23 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-23 inhibits renal tubular phosphate transport. This gene was identified by its mutations associated with autosomal dominant hypophosphatemic rickets (ADHR), an inherited phosphate wasting disorder. Abnormally high level expression of FGF23 was found in oncogenic hypophosphatemic osteomalacia (OHO), a phenotypically similar disease caused by abnormal phosphate metabolism. Mutations FGF23 have also been shown to cause familial tumoral calcinosis with hyperphosphatemia.
Keywords: | Tumor-derived hypophosphatemia-inducing factor, HYPF, ADHR, HPDR2, PHPTC, FGF23, FGF-23, Fibroblast Growth Factor-23. |
Supplier: | Biomol GmbH |
Supplier-Nr: | 97444 |
Properties
Application: | WB |
Conjugate: | No |
Host: | E.coli |
Species reactivity: | human |
MW: | 8670 D |
Purity: | >90% |
Format: | Lyophilized |
Database Information
KEGG ID : | K22428 | Matching products |
UniProt ID : | Q9GZV9 | Matching products |
Gene ID | GeneID 8074 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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