Endothelial Monocyte Activating Polypeptide II (EMAPII), human recombinant (rHu EMAPII)

Endothelial Monocyte Activating Polypeptide II (EMAPII), human recombinant (rHu EMAPII)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
08556.5 5 µg - -

3 - 10 business days*

94.00€
08556.20 20 µg - -

3 - 10 business days*

208.00€
08556.1 1 mg - -

3 - 10 business days*

5,242.00€
 
Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of... more
Product information "Endothelial Monocyte Activating Polypeptide II (EMAPII), human recombinant (rHu EMAPII)"
Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated polypeptide chain containing 166 amino acids.
Keywords: AIMP1, EMAP2, EMAP-2, EMAPII, SCYE1, Multisynthetase complex auxiliary component p43, Endothelial monocyte-activating polypeptide 2, EMAP-II, p43
Supplier: Biomol GmbH
Supplier-Nr: 08556

Properties

Application: Cell culture
Conjugate: No
Host: E.coli
Species reactivity: human
MW: 18300 D
Purity: >98%
Format: Lyophilized

Database Information

KEGG ID : K15437 | Matching products
UniProt ID : Q12904 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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