4-1BB Receptor, His Tag, human recombinant (rHu4-1BBr-His)

4-1BB Receptor, His Tag, human recombinant (rHu4-1BBr-His)
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
97392.5 5 µg - -

3 - 10 business days*

70.00€
97392.20 20 µg - -

3 - 10 business days*

180.00€
97392.1 1 mg - -

3 - 10 business days*

-
 
Human recombinant 4-1BBR produced in E.coli is a single, non-glycosylated polypeptide chain... more
Product information "4-1BB Receptor, His Tag, human recombinant (rHu4-1BBr-His)"

Human recombinant 4-1BBR produced in E.coli is a single, non-glycosylated polypeptide chain containing 193 amino acids (18-186) and having a molecular mass of 20kDa. 4-1BBR is fused to a 24 amino acid His-tag at N-terminus. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.

Keywords: Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor T-cell, antigen 4-1BB homolog, T-cell antigen ILA, CD137 antigen, CDw137, ILA, 4-1BB, MGC2172, 4-1BBR, TNFRSF9.
Supplier: Biomol GmbH
Supplier-Nr: 97392

Properties

Application: Bioassay
Conjugate: No
Expressed in: E.coli
Origin: Human
MW: 20000 D
Purity: >90%
Format: Solution

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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