Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
F4102.100 | 100 mg | - | - |
3 - 19 business days* |
280.00€
|
||
F4102.1 | 1 g | - | - |
3 - 19 business days* |
719.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The product of the AHSG gene is commonly referred to as fetuin in species other than the human.... more
Product information "Fetuin alpha-2 Heremans-Schmid Glycoprotein (FHSG), Bovine"
The product of the AHSG gene is commonly referred to as fetuin in species other than the human. The first fetal plasma protein to be described was fetuin, which was purified from fetal and newborn calf serum by Pedersen in 1944. Fetuin was subsequently shown to be a very abundant plasma protein in fetal cattle, sheep, pig, and goat, and also to be present in humans and rodents. Fetuins are proteins, which are made in the liver and secreted into the blood. They belong to a large group of binding proteins mediating the transport and availability of a wide variety of substances (drugs, hormones, fatty acids, vitamins etc) in the blood. The best known representative of these carrier proteins is serum albumin, the most abundant protein in the blood plasma of adult animals. Fetuin is more abundant in fetal blood, hence the name fetuin (from lat. fetus). Fetal calf serum contains more fetuin than albumin, while adult serum contains more albumin than fetuin. Human fetuin is synonymous with 2-HS-Glycoprotein (genetic symbol AHSG), a2-HS, A2HS, AHS, HSGA and fetuin-A. Fetuin-A exists as a single copy gene in the human and mouse genomes. A closely related gene, fetuin-B also exists in the human, rat and mouse genomes. Like fetuin-A fetuin-B is made predominantly by the liver and to a lesser extent by a number of secretory tissues. Fetuins exist it in all vertebrate genomes including fish and reptiles. Thus fetuins belong to the cystatin superfamily of proteins. Fetuin relatives within this superfamiliy are the histidine- rich glycoprotein (HRG) and kininogen (KNG). Fetuin-A deficiency dramatically increased the calcification proneness of these mice in that all mice sponteneously calcified throughout their body even without mineral-rich diet or surgical tissue trauma. Therefore Fetuin A is regarded as a potent inhibitor of systemic calcification. Fetuins have been implicated in several diverse functions, including osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors, and response to systemic inflammation. , Fetuin is a mixture of proteins containing a wider range of growth factors and attachments factors normally found in fetal calf serum. The major protein in fetuin is ~48.5Kd (74% protein, glycosylated). The other minor components of fetuins are alpha-1 and alpha-2 globulins and variety of growth factors such as IGF- 1/2 and FGFs. Fetuins, along with Transferrin, selenium and insulin, have been used in serum-free defined media formulations to increase cell attachment and growth. Fetuin is also an effective serine protease and it may improve cellular viability by inhibiting several proteases. CAS No: 9014-81-7, Source: Fetal bovine serum, Molecular Weight: 48.4kD, Appearance: Supplied as a white to light yellow powder, Solubility (Color at 1mg/ml): Colorless to faint yellow, Solubility (Turbidity at 1mg/ml): Clear to slightly hazy, Moisture: <7%, Free N-Acetyl Neuraminic Acid: <0.3%, Total N-Acetyl Neuraminic Acid: >5%, Nitrogen: 12-15%, Virus: BRSV, BPV, Reovirus, Rabies, BTV, VSV, P13 and BVDV:, Absent, Mycoplasma: None Detected, Endotoxin (Kinetic LAL): <5EU/mg, Total Microbial Count: <100cfu/g, Agarose Electrophoresis: Conforms, Cell Culture: Passes, Storage/Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 6 months after receipt. Certificate of Origin: The raw animal product used in the manufacturing of Fetuin is derived from a USDA licensed slaughterhouse in New Zealand where there have been no reported cases of bovine spongiform encephalopathy (BSE). The age of the bovine raw material is less than 3 years. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
Supplier: | United States Biological |
Supplier-Nr: | F4102 |
Properties
Conjugate: | No |
Species reactivity: | bovine |
Format: | Molecular Biology Grade |
Database Information
CAS : | 9014-81-7| Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed