N-Desmethylclobazam

N-Desmethylclobazam (Cay-18564) is an analytical reference material that is structurally categorized as a benzodiazepine. It is a major active metabolite of clobazam, produced primarily by the action of cytochrome P450 isoform 3A4. N-Desmethylclobazam positively modulates GABAA receptors (EC50s range from 98 to 151 µM, depending on subunit configuration). This product is intended for research and forensic applications.Formal Name: 8-chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione. CAS Number: 22316-55-8. Molecular Formula: C15H11ClN2O2. Formula Weight: 286.7. Purity: >98%. Formulation: (Request formulation change), A neat solid. SMILES: ClC1=CC(N(C2=CC=CC=C2)C(C3)=O)=C(C=C1)NC3=O. InChi Code: InChI=1S/C15H11ClN2O2/c16-10-6-7-12-13(8-10)18(11-4-2-1-3-5-11)15(20)9-14(19)17-12/h1-8H,9H2,(H,17,19). InChi Key: RRTVVRIFVKKTJK-UHFFFAOYSA-N.