JWH 424

JWH 018 is a synthetic cannabinoid (CB) that potently activates the central CB1 and peripheral CB2 receptors (Ki = 9.0 and 2.94 nM, respectively). This cannabimimetic compound has frequently been found in herbal blends. JWH 424 is an 8-bromonaphthyl derivative of JWH 018 which shows a reduced selectivity for CB1 over CB2 (Ki = 20.9 and 5.4 nM, respectively). The properties of this compound in vivo are not known. This product is intended for forensic and research applications.Formal Name: (8-bromonaphthalen-1-yl)(1-pentyl-1H-indol-3-yl)methanone. CAS Number: 1366068-04-3. Molecular Formula: C24H22BrNO. Formula Weight: 420.3. Purity: >98%. Formulation: (Request formulation change), A solution in methanol. Solubility: DMF: 5 mg/ml, DMSO: 5 mg/ml, Ethanol: 30 mg/ml, Methanol: 5 mg/ml. lambdamax: 224, 315 nm. SMILES: O=C(C1=CN(CCCCC)C2=C1C=CC=C2)C3=C4C(C=CC=C4Br)=CC=C3. InChi Code: InChI=1S/C24H22BrNO/c1-2-3-6-15-26-16-20(18-11-4-5-14-22(18)26)24(27)19-12-7-9-17-10-8-13-21(25)23(17)19/h4-5,7-14,16H,2-3,6,15H2,1H3. InChi Key: QXZYVJRMQVOOEQ-UHFFFAOYSA-N.