357 products were found matching "K04277"!

Delta9-THCP-d3 (CRM) (Cay-44430) is intended for use as an internal standard for the quantification of Delta9-THCP (Cay-33691, Cay-41267, Cay-30171) by GC- or LC-MS. Delta9-THCP is categorized as a phytocannabinoid and has been found in Cannabis. Delta9-THCP-d3 is regulated as a Schedule I compound in the United...

N-Arachidonoyl dopamine (NADA) is an arachidonoyl amino acid and cannabinoid (CB) receptor 1 agonist (Ki = 250 nM in rat brain membranes, which highly express CB1 receptors). It is selective for CB1 over CB2 receptors (Ki = 12,000 nM in rat spleen membranes, which highly express CB2 receptors). NADA induces...

AM251 is a cannabinoid 1 (CB1) receptor 1 antagonist. It binds to CB1 receptors in rat forebrain membrane preparations (Ki = 7.5 nM) and is selective over CB2 receptors in mouse spleen preparations (Ki = 2,290 nM) in radioligand binding assays. AM251 inhibits GTPgammaS binding induced by the CB receptor agonist CP...

The cannabinoid receptor CNR1 is Gs-coupled GPCRs expressed in primarily CNS and some peripheral neurones, particularly prevalent in basal ganglia, hippocampus, cerebellum, cerebral cortex and also presented in some non-neuronal cells and tissues, for example leukocytes and testis. A shorter human splice variant...

ADB-5'F-BUTINACA (Cay-37761) is an analytical reference standard categorized as a synthetic cannabinoid. This product is intended for research and forensic applications.Formal Name: (S)-N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-butyl-5-fluoro-1H-indazole-3-carboxamide. Molecular Formula: C18H25FN4O2. Formula...

The CB1 receptor is a G-protein coupled receptor that binds the active component of cannabis, Delta9-tetrahydrocannabinol. This antibody has been raised against the C-terminal (amino acids 461-472) intracellular region of the human CB1 receptor and can be used for western blotting. Human and rat CB1 receptors...

The CB1 receptor and the splice variant CB1a are localized mainly in the brain. The CB1 receptor is a G-protein coupled receptor that binds the active component of cannabis, Delta9-tetrahydrocannabinol. Human and rat CB1 receptors exhibit 97.3% homology at the amino acid level over the complete protein, and 100%...

Rimonabant is a cannabinoid 1 (CB1) receptor antagonist (Ki = 5.6 nM). It is selective for CB1 over CB2 receptors (Ki = >1,000 nM), as well as a panel of 37 other receptors and channels (IC50s = >1,000 nM). Rimonabant (10 µM) inhibits phytohemagglutinin-induced proliferation of isolated human peripheral blood...

9(R)-Hexahydrocannabinol (CRM) (Cay-37913) is a certified reference material that is structurally similar to known phytocannabinoids. 9(R)-Hexahydrocannabinol induces immobility, severe stupor, ataxia, full ptosis, and crouched posture, markers of psychotropic activity, in rhesus monkeys. This product is intended...

R-1 methanandamide is a potent cannabinoid (CB) receptor 1 agonist in the methanandamide series. It is selective for CB1 over CB2 receptors with Ki values ranging from 17.9 to 28.3 and 815 to 868 nM, respectively.{7912, 10685} R-1 methanandamide is more potent than arachidonoyl ethanolamide (AEA, Cay-90050). In...

2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor. The congener of 2-AG in which a linoleoyl group replaces the arachidonoyl group is 2-linoleoyl glycerol (2-LG), and this compound also appears in vivo in...

JD5037 is an inverse agonist of peripheral cannabinoid 1 (CB1) receptors (Ki = 0.35 nM). It displays >700-fold selectivity for CB1 over CB2, >1,000-fold selectivity over a panel of 70 receptors, transporters, and ion channels, and low blood-brain barrier penetrance. JD5037 is orally bioavailable and reduces food...