JWH 302

JWH 302 (Cay-10722) is a cannabimimetic indole that shows 5-fold selectivity for the central cannabinoid (CB1) receptor with a Ki value of 17 nM compared to the peripheral cannabinoid (CB2) receptor (Ki = 89 nM). JWH 302 stimulates GTPgammaS binding of CB1 and CB2 receptors with EC50 values of 29.3 and 24.4 nM, respectively.Formal Name: 2-(3-methoxyphenyl)-1-(1-pentyl-1H-indol-3-yl)-ethanone. CAS Number: 864445-45-4. Molecular Formula: C22H25NO2. Formula Weight: 335.4. Purity: >95%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2) (1:2): 0.33 mg/ml. lambdamax: 210, 245, 306 nm. SMILES: O=C(CC1=CC(OC)=CC=C1)C2=CN(CCCCC)C3=CC=CC=C32. InChi Code: InChI=1S/C22H25NO2/c1-3-4-7-13-23-16-20(19-11-5-6-12-21(19)23)22(24)15-17-9-8-10-18(14-17)25-2/h5-6,8-12,14,16H,3-4,7,13,15H2,1-2H3. InChi Key: XZVYWLVYUAQEIM-UHFFFAOYSA-N.