JWH 030

JWH 030 (Cay-10831) is a naphthoyl pyrrole cannabimimetic which activates the CB1 receptor (EC50 = 30.5 nM for rat, Ki = 87 nM for mouse) better than CB2 (EC50 = 552 nM for human CB2). JWH 030 is quite potent in vivo in the mouse spontaneous activity and tail flick (antinociception) assays (ED50 = 26.8 µM/kg). It also dose-dependently inhibits electrically-induced contractions of the mouse vas deferens (IC50 = 3.38 nM). This product is intended for forensic or research purposes.Formal Name: 1-naphthalenyl(1-pentyl-1H-pyrrol-3-yl)-methanone. CAS Number: 162934-73-8. Molecular Formula: C20H21NO. Formula Weight: 291.4. Purity: >98%. Formulation: (Request formulation change), A solution in methanol. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 20 mg/ml, Ethanol:PBS (pH 7.2) (1:1): Insouble, PBS (pH 7.2): Insouble. lambdamax: 217 nm. SMILES: O=C(C1=CN(CCCCC)C=C1)C2=C(C=CC=C3)C3=CC=C2. InChi Code: InChI=1S/C20H21NO/c1-2-3-6-13-21-14-12-17(15-21)20(22)19-11-7-9-16-8-4-5-10-18(16)19/h4-5,7-12,14-15H,2-3,6,13H2,1H3. InChi Key: VPBJQDBKZSHCPC-UHFFFAOYSA-N.