JWH 018 N-(1,1-dimethylpropyl) isomer

JWH 018 is a synthetic cannabinoid (CB) that potently activates the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors (Ki = 9.0 and 2.94 nM, respectively). This cannabimimetic compound has frequently been found in herbal blends. JWH 018 N-(2,2-dimethylpropyl) isomer differs from JWH 018 structurally by having a 1,1-dimethylpropyl group, rather than a pentyl chain, extending from the indole group. The biological activities of this compound have not been characterized. This product is intended for forensic purposes.Formal Name: [1-(1,1-dimethylpropyl)-1H-indol-3-yl]-1-naphthalenyl-methanone. CAS Number: 1358118-35-0. Molecular Formula: C24H23NO. Formula Weight: 341.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 10 mg/ml, Ethanol: 20 mg/ml. lambdamax: 218, 245, 313 nm. SMILES: O=C(C1=CN(C(CC)(C)C)C2=C1C=CC=C2)C3=C4C(C=CC=C4)=CC=C3. InChi Code: InChI=1S/C24H23NO/c1-4-24(2,3)25-16-21(19-13-7-8-15-22(19)25)23(26)20-14-9-11-17-10-5-6-12-18(17)20/h5-16H,4H2,1-3H3. InChi Key: RAHXKESFWHOCTB-UHFFFAOYSA-N.