Desalkylflurazepam

Desalkylflurazepam (Cay-18484) is an analytical reference material that is structurally categorized as a benzodiazepine. It is an active metabolite of several benzodiazepines, including flurazepam (Cay-18160), flutoprazepam, fludiazepam, midazolam, and quazepam. Desalkylflurazepam inhibits L-type voltage-gated calcium channels (Cav, IC50s = 55 and 37 µM for Cav1.2 and 1.3, respectively) by positively modulating GABAA receptors. It can be detected in urine, serum, and meconium by LC-MS/MS. This product is intended for research and forensic applications.Formal Name: 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one. CAS Number: 2886-65-9. Molecular Formula: C15H10ClFN2O. Formula Weight: 288.7. Purity: >98%. Formulation: (Request formulation change), A neat solid. SMILES: ClC(C=C1)=CC2=C1NC(CN=C2C3=CC=CC=C3F)=O. InChi Code: InChI=1S/C15H10ClFN2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20). InChi Key: UVCOILFBWYKHHB-UHFFFAOYSA-N.