AM1248

AM1248 is an adamantoylindole derivative with an N-methylpiperidin-2-ylmethyl substitution at the indole 1-position. It reportedly acts as a moderately potent agonist for both the central CB1 and peripheral CB2 cannabinoid receptors (Kis = 11.9 and 4.8 nM, respectively). A related compound, 1-pentyl-3-(1-adamantoyl)indole, along with another synthetic cannabinoid, AM679, was identified as having been sold as a cannabinoid herbal blend known as "smart products" in Hungary in 2011.Formal Name: [1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]tricyclo[3.3.1.13,7]dec-1-yl-methanone. CAS Number: 335160-66-2. Molecular Formula: C26H34N2O. Formula Weight: 390.6. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 14 mg/ml, DMF:PBS (pH 7.2) (1:4): 0.25 mg/ml, DMSO: 10 mg/ml, Methanol: 1 mg/ml. lambdamax: 214, 242, 297 nm. SMILES: O=C(C1(C2)C[C@@H]3C[C@H](C1)C[C@H]2C3)C4=CN(CC5N(C)CCCC5)C6=C4C=CC=C6. InChi Code: InChI=1S/C26H34N2O/c1-27-9-5-4-6-21(27)16-28-17-23(22-7-2-3-8-24(22)28)25(29)26-13-18-10-19(14-26)12-20(11-18)15-26/h2-3,7-8,17-21H,4-6,9-16H2,1H3/t18-,19+,20-,21?,26?. InChi Key: JRECAXBHMULNJQ-IYINYKJGSA-N.