6beta-Naltrexol

6beta-Naltrexol
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay15896-1 1 mg -

6 - 10 business days*

109.00€
Cay15896-5 5 mg -

6 - 10 business days*

477.00€
 
6beta-Naltrexol (Cay-15896) is an analytical reference material that is structurally categorized... more
Product information "6beta-Naltrexol"
6beta-Naltrexol (Cay-15896) is an analytical reference material that is structurally categorized as an opioid. It is the major metabolite of naltrexone (Cay-ISO60192, Cay-15520). Unlike naltrexone, which acts as a µ-receptor antagonist or inverse agonist, 6beta-naltrexol is a neutral opioid antagonist. 6beta-Naltrexol binds the µ-opioid receptor more potently than naloxone (Cay-ISO60191, Cay-15594) or naltrexone (Kis = 94, 420, and 265 pM, respectively) but is ~100-fold less effective at blocking morphine-modulated pain in vivo, as assessed using the mouse hotplate test. This product is intended for research and forensic applications.Formal Name: (5alpha,6beta)-17-(cyclopropylmethyl)-4,5-epoxy-morphinan-3,6,14-triol. CAS Number: 49625-89-0. Molecular Formula: C20H25NO4. Formula Weight: 343.4. Purity: >98%. Formulation: (Request formulation change), A neat solid. SMILES: O[C@]12[C@]3(CCN(CC4CC4)[C@@H]2C5)[C@](OC6=C3C5=CC=C6O)([H])[C@H](O)CC1. InChi Code: InChI=1S/C20H25NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,14-15,18,22-24H,1-2,5-10H2/t14-,15-,18+,19+,20-/m1/s1. InChi Key: JLVNEHKORQFVQJ-PYIJOLGTSA-N.
Keywords: 6beta-hydroxy Naltrexone, (5alpha,6beta)-17-(cyclopropylmethyl)-4,5-epoxy-morphinan-3,6,14-triol
Supplier: Cayman Chemical
Supplier-Nr: 15896

Properties

Application: Analytical reference material, Opioid, Major naltrexone metabolite
MW: 343.4 D
Formula: C20H25NO4
Purity: >98%
Format: Solid

Database Information

CAS : 49625-89-0| Matching products
KEGG ID : K04215 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H400, H410
P Phrases: P273, P391, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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