374 products were found matching "K04215"!

Description: OPRM1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 47.6 kDa and the accession number is P35372.

Small compounds (drugs or peptides) are not sufficiently complex by themselves to induce an immune response or be processed in a manner that elicits production of specific antibodies. For antibody production to be successful with small antigens, they must be chemically conjugated with immunogenic carrier proteins...

Naloxone (hydrochloride) (CRM) (Cay-ISO60191) is a certified reference material categorized as an opioid antagonist. Formulations containing naloxone have been used as antidotes for opioid overdose and the prevention of overdose. This product is intended for research and forensic applications.Formal Name:...

A mu-opioid agonist that is an antidiarrhoeal drug which inhibits intestinal motility and secretion. It has been shown to suppress the calcium-influx in dorsal root ganglion neurons.

A µ- and kappa-opioid receptor antagonist (Kis = 0.91 and 1.03 nM, respectively, in CHO membranes expressing the human receptors), selective for µ- and kappa-opioid receptors over delta-opioid receptors (Ki = 13.26 nM in CHO membranes expressing the human receptors), decreases self-administration of alcohol in...

Naloxonazine is a µ-opioid receptor antagonist (Ki = 0.054 nM in a radioligand binding assay). It is selective for µ-opioid over kappa- and delta-opioid receptors (Kis = 11 and 8.6 nM, respectively, in radioligand binding assays) and selectively binds to high-affinity µ1-opioid over µ- and delta-opioid receptors...

DAMGO is a selective peptide agonist of the µ-opioid receptor (Kis = 1.18, 1,430, and 213 nM for human µ-, delta-, and kappa-opioid receptors, respectively). DAMGO displays higher efficacy than morphine (Cay-ISO60147) for µ-opioid-induced nociception in rats.Formal Name:...

PZM21 is a µ-opioid receptor agonist (Ki = 1.1 nM). It is selective for µ- over kappa- and delta-opioid receptors (Kis = 18 and 506 nM, respectively). PZM21 induces Gi/o signaling (EC50 = 4.6 nM in HEK293T cells expressing human receptors) but has no detectable activity in a beta-arrestin2 recruitment assay. In...

Despropionyl para-fluorofentanyl (Cay-20104) is an analytical reference material that is structurally similar to known opioids. Despropionyl para-fluorofentanyl is a metabolite of FIBF (Cay-19795, Cay-19313), a precursor in the synthesis of para-fluorofentanyl, and a potential impurity in para-fluorofentanyl...

Naloxone-d5 (CRM) (Cay-18274) is a certified reference material intended for use as an internal standard for the quantification of naloxone (Cay-ISO60191, Cay-15594) by GC- or LC-MS. Naloxone is categorized as an opioid antagonist. Formulations containing naloxone have been used as antidotes for opioid overdose and...

O-Desmethyl-cis-tramadol (hydrochloride) (CRM) (Cay-18751) is a certified reference material that is structurally categorized as an opioid. It is the main metabolite of cis-tramadol (Cay-ISO60149, Cay-15919). O-Desmethyl-cis-tramadol has ~400-500-fold higher affinity for µ-opioid receptors than the parent compound....

SR 17018 is an orally bioavailable and brain-penetrant agonist of µ-opioid receptors. It is functionally selective for G protein-coupled receptor signaling (EC50 = 97 nM for GTPgammaS binding in CHO cells expressing µ-opioid receptors) over beta-arrestin 2 recruitment (EC50 = >10,000 nM) at the µ-opioid receptor. SR...