Tigloyl-L-carnitine (chloride)

Tigloyl-L-carnitine is a short-chain acylcarnitine composed of tiglic acid and L-carnitine (Cay-21489). Plasma levels of tigloyl-L-carnitine are increased in several melanoma mouse xenograft models compared with non-tumor bearing mice. Tigloyl-L-carnitine levels are increased in dried blood spots from neonates with mitochondrial acetyl-CoA acetyltransferase (T2) deficiency, an inborn error of isoleucine metabolism characterized by ketoacidosis.Formal Name: 3-carboxy-N,N,N-trimethyl-2-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]-1-Propanaminium, inner salt, monochloride. Synonyms: CAR 5:1, C5:1 Carnitine, L-Carnitine tigloyl ester, L-Carnitine tiglyl ester, L-Tigloylcarnitine, L-Tiglylcarnitine. Molecular Formula: C12H22NO4 . Cl. Formula Weight: 279.8. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: Soluble, DMSO: Soluble, Methanol: Soluble. SMILES: OC(C[C@H](C[N+](C)(C)C)OC(/C(C)=C/C)=O)=O.[Cl-]. InChi Code: InChI=1S/C12H21NO4.ClH/c1-6-9(2)12(16)17-10(7-11(14)15)8-13(3,4)5,/h6,10H,7-8H2,1-5H3,1H/b9-6+,/t10-,/m1./s1. InChi Key: PNDHRANMFFUOLD-SMQYOCSUSA-N.