Azelaoyl PAF

Azelaoyl PAF
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay60924-500 500 µg -

6 - 10 business days*

34.00€
Cay60924-1 1 mg -

6 - 10 business days*

64.00€
Cay60924-5 5 mg -

6 - 10 business days*

270.00€
Cay60924-10 10 mg -

6 - 10 business days*

473.00€
 
Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which... more
Product information "Azelaoyl PAF"
Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes via the nuclear receptor PPARgamma. One of these substances was recently isolated and purified from oxLDL, and identified as azelaoyl PAF. Azelaoyl PAF is a potent PPARgamma agonist which competes for the thiazolidinedione binding site. Azelaoyl PAF is more potent than 15-deoxy-Delta12,14-prostaglandin J2, and equipotent with rosiglitazone as a ligand for this receptor. Formal Name: 1-O-hexadecyl-2-O-(9-carboxyoctanoyl)-sn-glyceryl-3-phosphocholine. CAS Number: 354583-69-0. Molecular Formula: C33H66NO9P. Formula Weight: 651.9. Purity: >98%. Formulation: A solution in ethanol. Solubility: DMF: 33 mg/ml, DMSO: 8 mg/ml, Ethanol: 20 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: CCCCCCCCCCCCCCCCOC[C@@H](OC(CCCCCCCC(O)=O)=O)COP([O-])(OCC[N+](C)(C)C)=O. InChi Code: InChI=1S/C33H66NO9P/c1-5-6-7-8-9-10-11-12-13-14-15-16-20-23-27-40-29-31(30-42-44(38,39)41-28-26-34(2,3)4)43-33(37)25-22-19-17-18-21-24-32(35)36/h31H,5-30H2,1-4H3,(H-,35,36,38,39)/t31-/m1/s1. InChi Key: ZDFOCDTXDPKJKA-WJOKGBTCSA-N. Side Chain Carbon Sum: 25:0.
Keywords: 1-O-hexadecyl-2-O-(9-carboxyoctanoyl)-sn-glyceryl-3-phosphocholine
Supplier: Cayman Chemical
Supplier-Nr: 60924

Properties

Application: PPARgamma agonist
MW: 651.9 D
Formula: C33H66NO9P
Purity: >98%
Format: Solution

Database Information

CAS : 354583-69-0| Find alternatives
KEGG ID : K08530 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow. more
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Azelaoyl PAF"
Write a review
or to review a product.
Viewed