171 products were found matching "K08530"!

Rosiglitazone is an agonist of peroxisome proliferator-activated receptor gamma (PPARgamma). It activates PPARgamma1 and PPARgamma2 in reporter assays (EC50s = 30 and 100 nM, respectively). Rosiglitazone selectively activates chimeras containing the ligand-binding domains (LBDs) of PPARgamma over PPARalpha and...

BAY-4931 is a PPARgamma inverse agonist. It acts as an inverse agonist in a co-repressor reporter assay with a peptide from nuclear receptor co-repressor 2 (NCOR2, EC50 = 5.8 nM). BAY-4931 is selective for PPARgamma in reporter assays using CHO cells (IC50s = 0.14 and 0.4 nM for the mouse and human receptors,...

The peroxisome proliferator-activated receptor gamma (PPARgamma) is the nuclear receptor responsible for transducing the therapeutic activity of the thiazolidinediones. Thiazolidinediones are a group of structurally related synthetic PPARgamma agonists with antidiabetic actions in vivo. Rosiglitazone (BRL 49653) is...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PPAR-gamma. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat PPAR-gamma. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat PPAR-gamma....

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PPAR-gamma. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Cattle PPAR-gamma. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Cattle...

In the field of molecular biology, the peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes. Protein function: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty...

Troglitazone is a selective agonist of peroxisome proliferator-activated receptor gamma (PPARgamma, EC50s = 0.78 and 0.55 µM for the mouse and human receptors, respectively, in a transactivation assay). It is selective for PPARgamma over PPARalpha and PPARdelta, at which it is inactive at concentrations up to 10 µM....

XY-4 is a derivative of 1-palmitoyl-2-hydroxy-sn-glycero-3-PA (1-palmitoyl LPA, Cay-10010094) and an agonist of peroxisome proliferator-activated receptor gamma (PPARgamma). It induces reporter gene expression in RAW 264.7 macrophages expressing a peroxisome proliferator-response element (PPRE) when used at a...

Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors belonging to the large family of nuclear hormone receptors. There are three subtypes, PPARalpha, beta/delta, and gamma, which are expressed at variable levels in different tissues. The Cayman Chemical PPARgamma...

This formulation of 15-deoxy-Delta12,14-PGJ2 contains 90-95% of the trans,trans-Delta12,14 isomer, and 5-10% of other double bond isomers which have similar PPARgamma ligand activity (see Catalog No. 18570).Formal Name: 11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oic acid. CAS Number: 87893-55-8. Synonyms:...