9-oxo-10(E),12(E)-Octadecadienoic Acid

9-oxo-10(E),12(E)-Octadecadienoic acid (9-oxo ODA) is a natural agonist, abundant in tomatoes, that activates PPARalpha at 10-20 µM. It is produced from conjugated linoleic acid, which is also known to be a PPARalpha agonist. 9-oxo ODA increases the expression of genes regulated by PPARalpha in primary mouse hepatocytes, altering lipid metabolism.Formal Name: 9-oxo-10E,12E-octadecadienoic acid. CAS Number: 54232-58-5. Synonyms: 9-oxo ODA. Molecular Formula: C18H30O3. Formula Weight: 294.4. Purity: >90%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 16 mg/ml, DMSO: 16 mg/ml, Ethanol: 25 mg/ml, Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml. lambdamax: 276 nm. SMILES: O=C(/C=C/C=C/CCCCC)CCCCCCCC(O)=O. InChi Code: InChI=1S/C18H30O3/c1-2-3-4-5-6-8-11-14-17(19)15-12-9-7-10-13-16-18(20)21/h6,8,11,14H,2-5,7,9-10,12-13,15-16H2,1H3,(H,20,21)/b8-6+,14-11+. InChi Key: LUZSWWYKKLTDHU-SIGMCMEVSA-N.