107 products were found matching "K07294"!

HR68 is an anticancer agent and a derivative of the peroxisome proliferator-activated receptor (PPAR) agonist fenofibric acid (Cay-19262). It decreases the viability of LN-229 glioblastoma cells (IC50 = 1.17 µM). HR68 crosses the blood-brain barrier in a temozolomide-resistant orthotopic patient-derived xenograft...

N-Oleoyl-DPPE is an N-acyl-phosphatidylethanolamine (NAPE). It is a biosynthetic precursor to the endocannabinoid derivative and peroxisome proliferator-activated receptor alpha (PPARalpha) agonist oleoyl ethanolamide (OEA, Cay-90265).Formal Name: hexadecanoic acid,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PPARa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PPARa. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PPARa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PPARa. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat PPARa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat PPARa. Next,...

peroxisome proliferator activated receptor alpha(PPARA) Homo sapiens Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers, this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in...

The peroxisome proliferator-activated receptor alpha (PPARalpha) is a nuclear receptor that regulates the expression of genes involved in fatty acid metabolism, lipoprotein synthesis and metabolism, and inflammation. GW 6471 is an antagonist of PPARalpha (IC50 = 240 nM). It drives the displacement of coactivators...

Farnesyl alcohol is an isoprenoid that has been found in aromatic plants and has diverse biological activities. It is an agonist of peroxisome proliferator-activator receptor alpha (PPARalpha) and PPARgamma (EC50s = 5.5 and 28 µM, respectively, in a reporter assay using CV-1 cells) and increases the expression of...

Oleoyl ethanolamide (OEA) is an endogenous agonist for proliferator-activated receptor alpha (PPARalpha) that suppresses food intake, promotes lipolysis, and reduces weight gain in rodents. The biological effects of OEA are terminated by fatty-acid amide hydrolase and N-acylethanolamine-hydrolyzing acid amidase....

Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors belonging to the large family of nuclear hormone receptors. There are three subtypes, PPARalpha, beta/delta, and gamma, which are expressed at variable levels in different tissues. The Cayman Chemical PPARalpha...

Wy 14643 is an agonist of peroxisome proliferator-activated receptor alpha (PPARalpha). It selectively transactivates PPARalpha over PPARgamma in a reporter assay using CV-1 mouse fibroblasts when used at a concentration of 100 µM. Wy 14643 (2 mg/kg) decreases distal colon protein levels of IFN-gamma, TNF-alpha,...

Peroxisome proliferator-activated receptor-alpha (PPARalpha) is a ligand-activated transcription factor involved in the regulation of lipid homeostasis. Activation of PPARalpha results in expression of a variety of genes, particularly those involved in fatty acid beta-oxidation, binding, and transport. GW 7647 is a...