W140 (trifluoroacetate salt)

W140 is the inactive enantiomer of the sphingosine-1-phosphate receptor 1 (S1P1) antagonist W146 (Cay-10009109). It only weakly binds to S1P1 (Ki = 4.6 µM for the human receptor). W140 has been used as a negative control in vitro and in vivo in the study of S1P1 signaling.Formal Name: [3S-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid, mono(trifluoroacetate). CAS Number: 909725-64-0. Molecular Formula: C16H27N2O4P . CF3COOH. Formula Weight: 456.4. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: Ethanol: 0.15 mg/ml. lambdamax: 207, 246 nm. SMILES: CCCCCCC1=CC=CC(NC([C@@H](N)CCP(O)(O)=O)=O)=C1.FC(F)(C(O)=O)F. InChi Code: InChI=1S/C16H27N2O4P.C2HF3O2/c1-2-3-4-5-7-13-8-6-9-14(12-13)18-16(19)15(17)10-11-23(20,21)22,3-2(4,5)1(6)7/h6,8-9,12,15H,2-5,7,10-11,17H2,1H3,(H,18,19)(H2,20,21,22),(H,6,7)/t15-,/m0./s1. InChi Key: JDWCNCPWPLHFEX-RSAXXLAASA-N.